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SELECTBIO Conferences Lab-on-a-Chip, Microfluidics & Microarrays World Congress 2016

Michael Shuler's Biography



Michael Shuler, Samuel B. Eckert Professor of Engineering, Cornell University, President & CEO, Hesperos, Inc.

Michael L. Shuler is the Samuel B. Eckert Professor of Engineering in the Meing Department of Biomedical Engineering and in the School of Chemical and Biomolecular Engineering at Cornell University. Shuler has degrees in chemical engineering (BS, Notre Dame, 1969 and Ph.D., Minnesota, 1973) and has been at Cornell University since 1974. Shuler’s research includes development of “Body-on-a-Chip” for testing pharmaceuticals for toxicity and efficacy, creation of production systems for useful compounds, such as paclitaxel from plant cell cultures, and construction of whole cell models relating genome to physiology. Shuler is CEO and President of Hesperos, a company founded to implement the “Body-on-a-Chip” system. Shuler has been elected to the National Academy of Engineering and the American Academy of Arts and Science and is a fellow of numerous professional societies.

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Human “Body-on-a-Chip” Devices as Tool to Improve Drug Development

Wednesday, 28 September 2016 at 13:30

Add to Calendar ▼2016-09-26 00:00:002016-09-26 01:00:00Europe/LondonTitle to be Confirmed.Lab-on-a-Chip, Microfluidics and Microarrays World Congress 2016 in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com

Alternatives or supplements to the use of animals in preclinical drug development that better mimic human response should reduce costs and increase the number of FDA approved drugs at the end of clinical trials. We have constructed micro-physiological (or “Body-on-a-Chip”) devices constructed from a combination of human tissue engineered constructs, micro-fabricated devices and physiologically based pharmacokinetic (PBPK) models. These human surrogates are constructed on a low cost, robust “pumpless” platform. In addition to measuring viability and metabolic responses, we can measure functional outputs such as electrical activity and force generation using integrated sensors (in collaboration with J. Hickman, University of Central Florida). We will focus our discussion on development of key organ modules and their integration with each other to form a model of the human body.


Add to Calendar ▼2016-09-26 00:00:002016-09-28 00:00:00Europe/LondonLab-on-a-Chip, Microfluidics and Microarrays World Congress 2016Lab-on-a-Chip, Microfluidics and Microarrays World Congress 2016 in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com