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SELECTBIO Conferences Point-of-Care Diagnostics and Biosensors 2021

Jonathan D Posner's Biography

Jonathan D Posner, Professor of Mechanical Engineering & Chemical Engineering, University of Washington

Jonathan D. Posner is a professor joint in Mechanical Engineering and Chemical Engineering departments as well as adjunct professor in Family Medicine at University of Washington. He directs UW’s Engineering Innovation in Health program that focuses on developing technical solutions to pressing challenges in health and healthcare. Dr. Posner earned his Ph.D. (2001) degree in Mechanical Engineering at the UC Irvine, was a postdoctoral fellow at the Stanford University, and spent 18 months at the von Karman Institute for Fluid Mechanics. His research group works on diverse set of need-driven research projects including medical devices, point-of-care biochemical diagnostics, improved cookstoves for the developing world, and helmets that reduce the risk of concussion. He has 16 patents and patent applications and has founded two companies: VICIS focused on a football helmet that reduces the risk of concussion, and Phoresa focused on point-of-care diagnostics. Dr. Posner is a recipient of UW School of Medicine 2016 Inventor of the Year Award, the National Science Foundation CAREER Award, and recognized for his excellence in experimental research by the von Karman Institute for Fluid Dynamics in Belgium.

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Next Generation Point-of-Care Quantitative Molecular Tests For Blood-borne Viral Pathogens

Tuesday, 14 December 2021 at 17:30

Add to Calendar ▼2021-12-13 00:00:002021-12-13 01:00:00Europe/LondonTitle to be Confirmed.Point-of-Care Diagnostics and Biosensors 2021 in Coronado Island, CaliforniaCoronado Island,

Simple, self-administered molecular tests for blood-borne viruses remains a significant challenge due to the numerous sample preparation challenges, low detection limits required for viral pathogens, and difficulty in rapid quantification. Here we describe a paper membrane based NAAT with integrated sample preparation and amplification using recombinase polymerase amplification.  We quantify RNA using amplification nucleation site counting on paper membranes, a novel, rapid, and inexpensive analog to digital droplet isothermal amplification.  We discuss the challenges of detecting RNA targets in blood and alternative sample preparation strategies that can be integrated onto paper substrates. We demonstrate our POC viral diagnostic on HIV-1 virus and hepatitis C in whole blood.

Add to Calendar ▼2021-12-13 00:00:002021-12-15 00:00:00Europe/LondonPoint-of-Care Diagnostics and Biosensors 2021Point-of-Care Diagnostics and Biosensors 2021 in Coronado Island, CaliforniaCoronado Island,