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SELECTBIO Conferences Organ-on-a-Chip, Tissue-on-a-Chip Europe 2018

Ilka Maschmeyer's Biography

Ilka Maschmeyer, Senior Scientist, TissUse GmbH

Ilka Maschmeyer is a senior scientist at TissUse and a project head for the Multi-Organ-Chip cultures. Her focus is set on microfluidics and organs-on-a-chip since 2009. Since 2010 she is actively involved in the development of TissUse’s Multi-Organ-Chip platform for culture analysis of drug candidates, cosmetics, chemicals and consumer products. Ilka received her PhD in Bioengineering, from the Technische Universität Berlin, Department of Medical Biotechnology, followed by a postdoctoral training.

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Combining Organ Equivalents Using the Multi-Organ-Chip Technology

Tuesday, 5 June 2018 at 14:30

Add to Calendar ▼2018-06-05 14:30:002018-06-05 15:30:00Europe/LondonCombining Organ Equivalents Using the Multi-Organ-Chip TechnologyOrgan-on-a-Chip, Tissue-on-a-Chip Europe 2018 in Rotterdam, The NetherlandsRotterdam, The

The understanding of the bioavailability and metabolism of a chemical, either locally or systemically, is a key aspect in safety assessment. However, present in vitro and animal tests for drug development do not reliable predict the human outcome of tested drugs or substances because they are failing to emulate the organ complexity of the human body, leading to high attrition rates in clinical studies. For example, absorption, distribution, metabolism and excretion (ADME) are key determinants of efficacy and safety for therapeutic candidates. However, these systemic responses of applied substances are ignored in most in vitro tests. Here we present a universal microfluidic chip platform the size of a microscopic slide, consisting of an on-chip micro-pump and capable to interconnect different organ equivalents.

Add to Calendar ▼2018-06-05 00:00:002018-06-06 00:00:00Europe/LondonOrgan-on-a-Chip, Tissue-on-a-Chip Europe 2018Organ-on-a-Chip, Tissue-on-a-Chip Europe 2018 in Rotterdam, The NetherlandsRotterdam, The