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SELECTBIO Conferences 3D-Culture, Organoids and Organs-on-Chips 2021

Josué Sznitman's Biography

Josué Sznitman, Associate Professor, Technion – Israel Institute of Technology

Josué Sznitman is a Swiss, French and Israeli national. Sznitman graduated from MIT with a BSc in Mechanical Engineering (2002), followed by a Dr. Sc. (2008) from the ETH Zurich. In 2008, Sznitman joined the University of Pennsylvania as a Postdoctoral Fellow and moved to Princeton University as a Lecturer and Research Associate, appointed by the Princeton Council of Science & Technology. He joined the Dept. of Biomedical Engineering at the Technion (2010) and is currently an Associate Professor.

As a researcher, he directs the Technion Biofluids Laboratory with a stronghold in the areas of respiratory phenomena and drug delivery to the lungs. Sznitman has published over 75 peer-reviewed articles and is a co-inventor on several patents. He is an associate editor for Clinical Biomechanics (Elsevier), a member of the Editorial Board of Biomicrofluidics (AIP) and the Journal of Biomechanics (Elsevier), and serves as an Academic Editor for the journal PLoS One. Among his accolades, Sznitman was awarded the Young Investigator Award (2015) by the International Society of Aerosols in Medicine (ISAM) for a researcher under 40 and most recently the 2018 Emerging Scientist Award in Drug Delivery to the Lungs (The Aerosol Society, UK).

Josué  Sznitman Image

Advanced In vitro Inhalation Lung-on-Chip Platforms For Preclinical Research

Monday, 22 March 2021 at 09:45

Add to Calendar ▼2021-03-22 09:45:002021-03-22 10:45:00Europe/LondonAdvanced In vitro Inhalation Lung-on-Chip Platforms For Preclinical Research3D-Culture, Organoids and Organs-on-Chips 2021 in

With rapid advances, the development of lung-on-chip platforms is offering novel avenues for more realistic inhalation assays in pharmaceutical research, and an opportunity to depart from traditional in vitro lung assays. As advanced models capturing the cellular pulmonary make-up at an air-liquid interface (ALI), lung-on-chips emulate both morphological features and biological functionality of the airway barrier with the ability to integrate respiratory breathing motions and ensuing tissue strains. Such in vitro systems allow importantly to mimic more realistic physiological respiratory flow conditions, with the opportunity to integrate physically-relevant transport determinants of aerosol inhalation therapy, i.e. recapitulating the pathway from airborne flight to deposition on the airway lumen. In this presentation, we discuss recent developments in our group on devising such advanced human-relevant lung-on-chip models that mimic in situ-like inhalation assays with endpoints geared at cytotoxicity, respiratory diseases and therapies.

Add to Calendar ▼2021-03-22 00:00:002021-03-23 00:00:00Europe/London3D-Culture, Organoids and Organs-on-Chips 20213D-Culture, Organoids and Organs-on-Chips 2021 in