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SELECTBIO Conferences Circulating DNA, Circulating RNA, Circulating Tumor Cells, Circulating Proteins

Mei Wu's Biography

Mei Wu, Associate Professor, Mass General Hospital (MGH)/Harvard Medical School

Dr. Mei X. Wu is an associate professor in the Wellman Center for Photomedicine, Massachusetts General Hospital (MGH) and Department of Dermatology at Harvard Medical School (HMS). She received her Ph.D. from Utah State University in 1992 and did her postdoctoral training at Massachusetts Institute of Technology (MIT) and Dana-Farber Cancer Institute, HMS. Her most recent research areas are focused on new technology development including laser-based vaccine adjuvants, lesion-free and painless skin vaccination, detection of plasma biomarkers via laser-treated skin by surface modified microneedle arrays, and therapeutic potentials of noninvasive low level light for thrombocytopenia.

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Sample-Free Detection of Blood Biomarkers via Laser-Treated Skin

Tuesday, 22 March 2016 at 15:00

Add to Calendar ▼2016-03-22 15:00:002016-03-22 16:00:00Europe/LondonSample-Free Detection of Blood Biomarkers via Laser-Treated

The circulatory system is the center for coordination and communication of all organs in our body.  Monitoring any changes in its analytes and biomarkers could offer sufficient and timely point-of-care diagnosis. We will present how illumination of a tiny area of the skin with hemoglobin-preferably absorbent laser can increase the amount of circulating biomarkers in the upper dermis by more than 1,000-fold. When specific probe-coated microneedle arrays are applied into the laser-treated skin, the plasma biomarkers accumulated in the upper dermis can be reliably, accurately, and sufficiently captured as early as 15-30 min of the assay in a manner independent of a molecular mass of the biomarkers. The novel, minimally invasive approach may allow engineering small wearable devices for measuring multiple biomarkers simultaneously for point-of-care diagnosis.

Add to Calendar ▼2016-03-21 00:00:002016-03-22 00:00:00Europe/LondonCirculating DNA, Circulating RNA, Circulating Tumor Cells, Circulating