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SELECTBIO Conferences Epigenetics in Drug Discovery

Danette Daniels's Biography

Danette Daniels, Group Leader, Promega Corporation

Danette received her B.A. in Biochemistry from Columbia University, Ph.D. in Biophysics from Yale University, and completed a postdoctoral fellowship at Stanford University School of Medicine studying Wnt signaling and transcription. She has been at Promega Corporation for 12 years and is currently an R&D Group Leader of Functional Proteomics developing technologies to characterize intracellular interactions as well as focusing on advances in epigenetics research.

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Exploring the Function of Bivalent Epigenetic Inhibitors in Living Cells

Monday, 6 March 2017 at 14:15

Add to Calendar ▼2017-03-06 14:15:002017-03-06 15:15:00Europe/LondonExploring the Function of Bivalent Epigenetic Inhibitors in Living

Here we present studies on two different types of bivalent BET family inhibitors, bi-BET, a novel inhibitor which can simultaneously inhibit two bromodomains, and dBET1, an inhibitor which promotes degradation of BET family members via interactions with Cereblon E3 ligase.

Add to Calendar ▼2017-03-06 00:00:002017-03-07 00:00:00Europe/LondonEpigenetics in Drug