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SELECTBIO Conferences Antibodies in Drug Discovery

John McCafferty's Biography

John McCafferty, Founder & CEO, IONTAS Ltd

Pioneer and inventor of antibody-phage display and co-founder of Cambridge Antibody Technology. John established a highly proficient proteomics group at the Wellcome Trust Sanger Institute which developed cutting edge protein expression and high throughput recombinant antibody isolation.

More recently he has headed a research group within the Department of Biochemistry, University of Cambridge. The focus here was identifying anti-receptor antibodies with therapeutic potential in cancer indications.

In 2012 John formed IONTAS, a small innovative biotechnology company using phage display to develop novel antibody therapeutics. In addition IONTAS are developing novel technologies allowing discovery of IgG formatted antibodies directly from very large mammalian display libraries.

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Construction and Use of Large Antibody Libraries in Mammalian Cells

Tuesday, 9 February 2016 at 09:00

Add to Calendar ▼2016-02-09 09:00:002016-02-09 10:00:00Europe/LondonConstruction and Use of Large Antibody Libraries in Mammalian Cells Antibodies in Drug Discovery in Cambridge, UKCambridge,

This presentation demonstrates the construction and use of large libraries of antibodies and T cell receptors in mammalian cells. Library construction is facilitated by the use of site-specific nucleases such as TALE nucleases and Cas9/CRISPR.

Add to Calendar ▼2016-02-09 00:00:002016-02-10 00:00:00Europe/LondonAntibodies in Drug DiscoveryAntibodies in Drug Discovery in Cambridge, UKCambridge,