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SELECTBIO Conferences Extracellular Vesicles (EVs): Technologies & Biological Investigations

Joshua Welsh's Biography

Joshua Welsh, Research Fellow, National Cancer Institute (NCI), NCI

Dr Welsh is currently a Research Fellow within the Translational Nanobiology Section at the National Institutes of Health. Dr Welsh received his PhD from the University of Southampton where he worked with Thermo Fisher Scientific to develop a small particle flow cytometer and developed light scatter calibration methods. Since joining the Translational Nanobiology Section, his research has focused on developing a high-throughput, scalable, clinical pipeline for characterizing extracellular vesicles for their use as clinical biomarkers. This work has involved developing assays, standalone software, standardization methods, and multidimensional data analyses. Josh is a member-at-large of the ISEV Executive Board, associate editor of current protocols in cytometry, chair of the ISEV Rigor and Standardization: EV Reference Materials Task Force, Member of ISAC data committee, member of ISAC-ISEV-ISTH EV Flow Cytometry Working Group, and an ISAC Marylou Ingram scholar.

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Utilizing Flow Cytometry For Multi-Parametric Analysis

Tuesday, 14 December 2021 at 15:30

Add to Calendar ▼2021-12-14 15:30:002021-12-14 16:30:00Europe/LondonUtilizing Flow Cytometry For Multi-Parametric AnalysisExtracellular Vesicles (EVs): Technologies and Biological Investigations in Coronado Island, CaliforniaCoronado Island,

Extracellular vesicles (EVs) are sub-micron lipid spheres derived from cells. Interest in EVs is growing due to their potential applications in translational medicine, therapeutics, as well as their role in basic biology. Progress in the understanding of EVs has been hampered by the lack of equipment and standardization in the EV field. In recent years, the development of highly sensitive commercial flow cytometry platforms, along with societal initiatives, has led to flow cytometry being one of the most informative EV characterization methods. Our work at NIH has developed flow cytometry assays, standardization methods, and software for study of EVs at a single particle level and as part of multiplex analysis techniques. Our methods have allowed EV data to be reported in standard units allowing cross-platform data integration, with the ultimate aim of developing an EV atlas.

Add to Calendar ▼2021-12-13 00:00:002021-12-15 00:00:00Europe/LondonExtracellular Vesicles (EVs): Technologies and Biological InvestigationsExtracellular Vesicles (EVs): Technologies and Biological Investigations in Coronado Island, CaliforniaCoronado Island,