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SELECTBIO Conferences Lab-on-a-Chip and Microfluidics Europe 2020

Regina Luttge's Biography

Regina Luttge, Professor, Eindhoven University of Technology

Regina Luttge investigates and develops microsystems for medicine and biology applying emerging and established micro-nanofabrication methods to control systems’ properties at the nanoscale. Regina studied Applied Sciences in Germany and worked as an engineering researcher at Institut für Mikrotechnik Mainz (IMM GmbH) for nearly five years prior to starting her PhD studies in Microsystems Technologies at Imperial College, London, in 1999. In 2003 she received her PhD from the University of London on the development of fabrication technologies for micro-optical scanners. Switching her research interest to microfluidic systems, Luttge went on to work at the University of Twente’s MESA+ Institute for Nanotechnology, The Netherlands. Initially as a postdoc and later, when she received a Veni award by The Netherlands Organisation for Scientific Research (NWO) as an Assistant Professor in the Mesoscale Chemical Systems group. Receiving her second personal award (ERC Starting grant) by the European Research Council in 2011 empowered her to set up her own research line in microsystems for medicine and biology as an independent PI. In 2013, she moved her research line to the newly started Microsystems section at TU/e, where she was also appointed Associate Professor in the same year. Since 2018, she continuous her research activities within in the Microsystems section as Chair of Neuro-Nanoscale Engineering. Currently, she is the leader of CONNECT, a 5 years EU funded project conducting research to better understand Parkinson’s disease by means of Organ-on-a-Chip (OOC), specific microsystems recapitulating the in vivo microenvironment of human tissues in a dish. Besides education and research, Regina is passionate about spinning off new businesses from her academic activities, encouraging her students at all levels of their educational program to take part in the innovation chain.

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Nervous Systems-on-a-Chip: From Technology to Applied Biomedical Sciences

Wednesday, 9 September 2020 at 12:00

Add to Calendar ▼2020-09-09 12:00:002020-09-09 13:00:00Europe/LondonNervous Systems-on-a-Chip: From Technology to Applied Biomedical SciencesLab-on-a-Chip and Microfluidics Europe 2020 in Rotterdam, The NetherlandsRotterdam, The

Challenges in eavesdropping on the complex cell signaling of the human central nervous system is an essential driver for the development of advanced in vitro technologies, called Brain-on-a-Chip. Developments in Brain-on-a-Chip technology focus primarily on the implementation of cortical cells from human stem cell source in a 3D cultured microenvironment. The aim of a recently launched EU project CONNECT is to mimic the in vivo functions of the nervous system in one connected chip system. The creation of new neurodegenerative disease models in this project brings together the knowledge accumulated among neuroscientists, stem cell experts and engineers to investigate the origins and possible treatments for Parkinson's disease. In this presentation, we will discuss in detail the technical approach of a nervous system on a chip as a unique tool for modelling the neural pathway of connected tissues on the brain-gut axis. In addition to design criteria for these microliter-sized physiological cell culture systems, the presentation will focus on guidance of the growth process of axon protrusions and the local control of cell differentiation processes while maintaining physiological conditions.

Add to Calendar ▼2020-09-09 00:00:002020-09-10 00:00:00Europe/LondonLab-on-a-Chip and Microfluidics Europe 2020Lab-on-a-Chip and Microfluidics Europe 2020 in Rotterdam, The NetherlandsRotterdam, The