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SELECTBIO Conferences Exosomes & Liquid Biopsies Europe 2018

Nikolas Stoecklein's Biography

Nikolas Stoecklein, Professor, Experimental Surgical Oncology, Heinrich Heine University Düsseldorf

Nikolas Stoecklein is currently a Professor for Experimental Surgical Oncology at the Heinrich-Heine University Düsseldorf (HHU), Germany. His major research interests are minimal residual disease and early systemic disease in cancer. A current focus of his group is to improve CTC-based liquid biopsies. He pioneered Diagnostic Leukapheresis (DLA) for enhanced CTC detection and established workflows to parse CTCs comprehensively at the single cell level to get deeper insights into the biology of systemic progression and therapeutic resistance. Prior joining the HHU, Nikolas obtained post-doctoral training at the Institute of Immunology of the Ludwig-Maximilians-University Munich, Germany, in the group of Christoph Klein. He graduated from the University of Hamburg, Germany, in 1998 where he studied medicine.

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Diagnostic Leukapheresis (DLA) to Improve CTC-Based Liquid Biopsies

Wednesday, 24 October 2018 at 16:30

Add to Calendar ▼2018-10-24 16:30:002018-10-24 17:30:00Europe/LondonDiagnostic Leukapheresis (DLA) to Improve CTC-Based Liquid BiopsiesExosomes and Liquid Biopsies Europe 2018 in Rotterdam, The NetherlandsRotterdam, The

The direct access to systemically spread cancer cells is the true potential of CTC-based liquid biopsies. However, the major obstacle to implement CTC-based liquid biopsies into clinical routine applications is the extreme low concentration of CTCs and the minimal amount of investigated blood in standard CTC-tests. To tackle this problem, we introduced Diagnostic Leukapheresis (DLA), which resulted in an increase in CTC detection frequency and an escalation of the median CTC numbers. We hope that DLA, or similar approaches derived thereof, will advance the clinical utility of CTC-based liquid biopsies.

Add to Calendar ▼2018-10-24 00:00:002018-10-26 00:00:00Europe/LondonExosomes and Liquid Biopsies Europe 2018Exosomes and Liquid Biopsies Europe 2018 in Rotterdam, The NetherlandsRotterdam, The