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SELECTBIO Conferences Flow Chemistry Asia 2023

Shinichiro Fuse's Biography

Shinichiro Fuse, Professor, Nagoya University

Shinichiro Fuse has been a professor of chemistry at Nagoya University since 2019. He earned his B.S. degree in 2000 and his Ph.D. in 2005 from Tokyo Institute of Technology under the supervision of Prof. Takashi Takahashi. He was a researcher at ChemGenesis Incorporated between 2005 and 2006, and a postdoctoral fellow from 2006 to 2008 at Harvard University in the group of Prof. Daniel E. Kahne. In 2008, he joined the faculty at the Tokyo Institute of Technology as an assistant professor. He then moved to the Chemical Resources Laboratory at the same university as an associate professor in 2015. His research is aimed toward the development of efficient synthetic processes based on a deep understanding of organic chemistry using flow synthesis, automated synthesis, theoretical calculations, and machine-learning technologies.

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Rapid and Column-Chromatography-Free Flow-Peptide Chain Elongation

Thursday, 5 October 2023 at 11:15

Add to Calendar ▼2023-10-05 11:15:002023-10-05 12:15:00Europe/LondonRapid and Column-Chromatography-Free Flow-Peptide Chain ElongationFlow Chemistry Asia 2023 in Tokyo, JapanTokyo,

Peptides have become increasingly important as drugs. In this study, we developed rapid, mild and column-free peptide chain elongation via one-flow, three-component coupling approach using amino acid N-carboxy anhydride (NCA) which has both nucleophilicity and electrophilicity. The key to success was the rapid generation of acid chloride from amino acid and its rapid coupling with NCA via rapid dual activation.

Add to Calendar ▼2023-10-05 00:00:002023-10-06 00:00:00Europe/LondonFlow Chemistry Asia 2023Flow Chemistry Asia 2023 in Tokyo, JapanTokyo,