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SELECTBIO Conferences Organoids & Microphysiological Systems 2022

Shannon Mumenthaler's Biography

Shannon Mumenthaler, Assistant Professor of Medicine & Biomedical Engineering, University of Southern California, Ellison Institute

Shannon Mumenthaler, PhD, is an Assistant Professor of Medicine and Biomedical Engineering at the University of Southern California. She is also the Laboratory Director for the Ellison Institute of Transformative Medicine, which is a translational institute that bridges research and innovation by bringing together researchers, patients, and physicians dedicated to improving human health. Her multidisciplinary research program is focused on providing new insights into the significance of the physical and cellular microenvironment on colorectal cancer progression through the development and utilization of physiologically relevant, organ-dependent tumor models that allow for the characterization of cancer cell dynamics, and serves as a platform for testing specific therapeutic modalities.

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Cancer-on-a-Chip Model of Colorectal Cancer Progression

Wednesday, 14 December 2022 at 11:30

Add to Calendar ▼2022-12-14 11:30:002022-12-14 12:30:00Europe/LondonCancer-on-a-Chip Model of Colorectal Cancer ProgressionOrganoids and Microphysiological Systems 2022 in Long Beach, CaliforniaLong Beach,

The highly complex and evolving nature of cancer makes it challenging to study. Here we describe a microfluidic organ-on-chip platform, incorporating tissue-tissue interfaces and physical forces, to support novel interrogations of colorectal cancer progression. We will cover advancements made through combining organoids and an organ-on-chip model with high content imaging and mass spectrometry-based metabolomics, which provide measurements that capture spatial and temporal cancer cell dynamics. This work reveals important interactions between colorectal cancer cells and their microenvironment, which can be used to prevent or delay cancer progression.

Add to Calendar ▼2022-12-12 00:00:002022-12-14 00:00:00Europe/LondonOrganoids and Microphysiological Systems 2022Organoids and Microphysiological Systems 2022 in Long Beach, CaliforniaLong Beach,