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SELECTBIO Conferences EV-based Diagnostics, Delivery & Therapeutics

Juliane Nguyen's Biography

Juliane Nguyen, Associate Professor, University of North Carolina at Chapel Hill

Juliane Nguyen, Ph.D., is an Associate Professor in the Division of Pharmacoengineering and Molecular Pharmaceutics, School of Pharmacy, at the University of North Carolina at Chapel Hill. Her lab develops novel protein-, RNA-, and exosome-based biochemical and delivery platforms for treating myocardial infarction and cancer. Dr. Nguyen’s work has been recognized with the NYSTAR faculty award, the NSF CAREER Award (2018), the Young Innovator Award from the Biomedical Engineering Society (2019), and the AAPS Emerging Leader Award (2019). She received her PharmD and her Ph.D. in Pharmaceutical Sciences from the Philipps-University of Marburg (Germany), where she was mentored by Dr. Thomas Kissel. She then trained at UCSF under Dr. Frank Szoka, where she was a Deutsche Forschungsgemeinschaft Postdoctoral Fellow.

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Pharmacoengineered Extracellular Vesicles for Therapeutic Applications

Tuesday, 18 February 2020 at 10:00

Add to Calendar ▼2020-02-18 10:00:002020-02-18 11:00:00Europe/LondonPharmacoengineered Extracellular Vesicles for Therapeutic ApplicationsEV-based Diagnostics, Delivery and Therapeutics in Coronado Island, CaliforniaCoronado Island,

An increasing number of studies report that mesenchymal stem cell-derived exosomes have regenerative effects. However, the underlying molecular mechanisms of this are poorly characterized. Using microRNA profiling and network analysis, we identified the dominant biological processes and pathways modulated by exosomal miRNAs. Further, to improve upon the intrinsic biological effects of MSC exosomes, we have discovered novel biomaterials that allow highly efficient loading of exosomes with therapeutic cargoes including nucleic acids, paving the way for cell-free therapeutics in many diseases including cardiac regeneration after myocardial infarction.

Add to Calendar ▼2020-02-17 00:00:002020-02-18 00:00:00Europe/LondonEV-based Diagnostics, Delivery and TherapeuticsEV-based Diagnostics, Delivery and Therapeutics in Coronado Island, CaliforniaCoronado Island,