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SELECTBIO Conferences Bioprinting and Bioink Innovations for 3D-Tissues 2022

Gabriela Graziani's Biography

Gabriela Graziani, Researcher, Rizzoli Orthopaedic Institute in Bologna

Dr. Gabriela Graziani, is a Researcher at Rizzoli Orthopaedic Institute in Bologna (Italy), where she conducts research regarding materials science applied to orthopaedics, with a special focus on nanostructured materials and their combination with 3D printing and 3D bioprinting and on the development of new biomaterials from re-use of waste sources. She also carries out research on materials for cultural heritage conservation, with a specific reference to the development of consolidants and protectives for ancient stone, mortars and archaeological bone. She obtained her Master Degree (2012) and her PhD (2016) in Engineering at the University of Bologna, where she also served at as post-doc researcher. In 2014, she spent 6 months at Princeton University, as a Visiting Student Research Collaborator, under the supervision of prof. George Scherer. She has been adjunct professor of Ceramic Materials at the University of Bologna from 2016 to 2019. Her research was awarded with several prices including the ON-EORS award in 2021, a PhD thesis award and best poster presentations. Her entrepreneurial mindset was also awarded by a prize for start-up ideas (Program Reactor, Fondazione Golinelli, Bologna) and by a visiting and training period at the “Mind The Bridge Startup School” (San Francisco, CA). She is a member of the Young Investigators board of the European Orthopaedic Research Society (EORS). She served as scientific committee member, invited speaker, session co-chair and/or workshops organizer at international conferences, including the 2020 and 2021 annual meetings of the EORS, the meeting of the orthopaedic research society 2021, the 31st Annual Conference of the European Society for Biomaterials (ESB 2021) and the World Biomaterials Congress (WBC 2020). Currently, she is Principal Investigator of the project “A new strategy to address tumor relapses by nanostructured implantable devices”, financed by the Italian Ministry of Health, WP leader of projects funded by the Royal Society of Edinburgh, Scottish Funding Council and the Scottish Government (RSE Saltire International Collaboration Award) and by the Italian Ministry of Economy and Finance (5 x 1000 for Scientific Research) and key person of the Euronanomed Project “NANOVERTEBRA - Next generation antibacterial nanostructured osseointegrated customized vertebral replacement”.

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Additive Manufacturing and Nanomaterials-based Platforms For Bone Modeling and Regeneration: Controlling Cell Fate by Combined Compositional and Morphological Cues

Monday, 7 November 2022 at 15:00

Add to Calendar ▼2022-11-07 15:00:002022-11-07 16:00:00Europe/LondonAdditive Manufacturing and Nanomaterials-based Platforms For Bone Modeling and Regeneration: Controlling Cell Fate by Combined Compositional and Morphological CuesBioprinting and Bioink Innovations for 3D-Tissues 2022 in Boston, USABoston,

Bone is a hierarchical tissue, having complex morphology and composition. Hence, new approaches are needed to mimic its characteristics, to obtain bone models as well as for its regeneration. To fulfill these aims, a scaffold or models shall  reproduce as closely as possible the composition of native bone, because mimicking the native tissue permits boosting bone regeneration, and because bone apatite has a critical role in modulating the behavior of both healthy and tumor cells in the models. At the same time, morphological characteristics (i.e. porosity, surface morphology and roughness) are fundamental to determine the mechanical behavior of the model and to provide cues to which cells can react and that influence their morphology, adhesion, proliferation and differentiation. Here we propose new routes for obtaining bone-mimetic materials, by combining additive manufacturing techniques (3d printing and electrospinning) and plasma-assisted deposition of nano-structured coatings (Ionized Jet Deposition). By these techniques, we reproduce the characteristics of the native tissue and guide its regeneration, exploiting biomimicry, morphological and compositional cues and we study their interactions with healthy (MSCs) and tumor (SAOS-2) cells, for applications in bone regeneration and modeling.

Add to Calendar ▼2022-11-07 00:00:002022-11-08 00:00:00Europe/LondonBioprinting and Bioink Innovations for 3D-Tissues 2022Bioprinting and Bioink Innovations for 3D-Tissues 2022 in Boston, USABoston,