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SELECTBIO Conferences Circulating Biomarkers, Exosomes & Liquid Biopsy Europe 2022

Jan Brants's Biography

Jan Brants, Regional Sales Director - France Benelux, NanoView Biosciences

In his position at NanoView Biosciences, Jan supports and develops the growth of the ExoView platform for the characterization of exosomes and viruses in France, Belgium, Luxembourg, and the Netherlands. Jan holds a MSc degree in Biochemistry and a PhD degree in Medical Sciences from the University of Leuven, Belgium, followed by postdoctoral training in cancer and cell biology at the IGBMC in Strasbourg, France. Jan has been working in the life sciences and diagnostics industry for many years, occupying several positions including applications support, sales management and business development at the companies Millipore, Merck and Luminex, respectively.

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Purification-Free Measurement of Exosomes and Viruses Down to 20nm

Tuesday, 1 March 2022 at 17:30

Add to Calendar ▼2022-03-01 17:30:002022-03-01 18:30:00Europe/LondonPurification-Free Measurement of Exosomes and Viruses Down to 20nmCirculating Biomarkers, Exosomes and Liquid Biopsy Europe 2022 in Rotterdam, The NetherlandsRotterdam, The

Current analytical tools have detection limitations when used for exosome characterization due to their small size. Specifically, exosomes have fewer surface epitopes available and low-signal relative to background levels, especially in complex samples. Current workflows often require multiple measurement technologies that result in the inability to link phenotypic and physical characterization on individual EVs across a biologically relevant size range and down to the smallest of sizes present within many samples. In addition, sample purification often results in loss of sample and technique dependent biases. NanoView Biosciences has developed an imaging technique that allows individual EVs and viruses as small as 20nm to be characterized direct from sample with no purification in most cases. Physical characteristics such as size and EV count can be presented alongside phenotypic information at the single EV level. Low volumes of sample can be probed and a panel of up to 10 surface markers can be interrogated in parallel, in a single measurement. Lastly, through the addition of fluorescent labeling, three additional markers can be probed and colocalized across the existing panel of 10 markers. These capabilities make the tool ideally for basic EV research, biomarker discovery and the development of EV based liquid biopsies and therapeutics.

Add to Calendar ▼2022-03-01 00:00:002022-03-02 00:00:00Europe/LondonCirculating Biomarkers, Exosomes and Liquid Biopsy Europe 2022Circulating Biomarkers, Exosomes and Liquid Biopsy Europe 2022 in Rotterdam, The NetherlandsRotterdam, The