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SELECTBIO Conferences Bioprinting and Bioink Innovations for 3D-Tissues 2022

Jason Burdick's Biography

Jason Burdick, Bowman Endowed Professor, BioFrontiers Institute, University of Colorado Boulder

Jason A. Burdick, PhD is the Bowman Endowed Professor in the BioFrontiers Institute and Department of Chemical and Biological Engineering at the University of Colorado Boulder. Dr. Burdick’s research involves the design of new biomaterials that can be processed through fabrication methodologies to meet the needs of medicine, ranging from translational therapeutics to tissue models. Jason currently has over 280 peer-reviewed publications, he is on the editorial boards of Journal of Biomedical Materials Research A, Biofabrication, Bioengineering, and Advanced Healthcare Materials, and he is an Associate Editor for ACS Biomaterials Science & Engineering. He has been recognized through numerous awards such as a Packard Fellowship in Science and Engineering, an American Heart Association Established Investigator Award, the Clemson Award for Basic Science through the Society for Biomaterials, and the Acta Biomaterialia Silver Medal Award. Jason has also been elected as a Fellow of the American Institute for Medical and Biological Engineering, to the International College of Fellows of Biomaterials Science and Engineering, and as a Fellow of the National Academy of Inventors. Lastly, he has founded several companies to translate technology developed in his laboratory towards clinical application.

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Suspension Bath Printing to Guide Cell Organization in the Engineering of Tissue Constructs and Models

Monday, 7 November 2022 at 09:00

Add to Calendar ▼2022-11-07 09:00:002022-11-07 10:00:00Europe/LondonSuspension Bath Printing to Guide Cell Organization in the Engineering of Tissue Constructs and ModelsBioprinting and Bioink Innovations for 3D-Tissues 2022 in Boston, USABoston,

Biofabrication is an interdisciplinary field that has seen rapid technological advances that are important in the fabrication of engineered tissues, particularly with the incorporation of defined structures that drive tissue function. Our group is particularly interested in designing new materials and technologies to advance this field. For example, one approach is the printing of cells and materials into hydrogel suspension baths, which are shear-yielding materials that deform to receive printed structures anywhere in 3D space. Due to the complexity of this process, we are developing computational models that combine with new experimental tools to better describe and optimize this process across a range of inks and suspension baths. We are implementing suspension baths in the engineering of anisotropic tissues (e.g., meniscus), where inks are printed that contain short fibers that align due to shear forces during printing. When cells are incorporated (e.g., meniscal fibrochondrocytes), the aligned fibers guide cell and matrix with culture, resulting in the formation of anisotropic tissue constructs. Towards a disease model of myocardial infarction (MI), we transfer cellular spheroids into hydrogel suspension baths at high resolution, enabling their patterning and fusion into high-cell density microtissues. We bioprint iPSC-derived cardiac microtissue models with spatially controlled cardiomyocyte and fibroblast cell ratios to replicate the structural and functional features of scarred cardiac tissue (e.g., reduced contractility, irregular electrical activity) and use them to screen microRNA therapeutics. Such technologies are likely to make a major impact across wide biomedical fields.

Add to Calendar ▼2022-11-07 00:00:002022-11-08 00:00:00Europe/LondonBioprinting and Bioink Innovations for 3D-Tissues 2022Bioprinting and Bioink Innovations for 3D-Tissues 2022 in Boston, USABoston,