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SELECTBIO Conferences Organoids and Organs-on-Chips Europe 2022

Séverine Le Gac's Biography

Séverine Le Gac, Professor, Applied Microfluidics for Bioengineering Research, MESA+ Institute for Nanotechnology, University of Twente

Séverine Le Gac is Professor at the University of Twente, The Netherlands, where she leads a team called “Applied Microfluidics for BioEngineering Research – AMBER”. Séverine Le Gac received her Engineer degree in chemistry (specialization biology) from the ESPCI (Paris, France) in 2000 and her PhD cum laude in 2004 in life sciences from the University of Lille (France). She has about 20 years experience in the field of microfluidics focusing on bioanalytical, biological and medical applications. Her research interests focus on the use of microfluidic devices and organ-on-chip models for biological and medical applications, including experimentation on single cells, analysis of extracellular vesicles, cancer research, assisted reproductive technologies, and the incorporation of biomechanical cues in organ-on-chip models. Prof. Le Gac is Associate Editor of the Lab on a chip journal (RSC), co-editor-in-chief of the Organs-on-a-chip journal (Elsevier) and part of the advisory board of the Journal of Micromechanics and Microengineering (IOP Publisher). Since 2018, she has also been Member of the Director Board of the CBMS Society (Chemical and Biological Microsystem Society;, of which she is currently the vice-president.

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Organ-on-Chip Models For Medical Applications

Wednesday, 22 June 2022 at 09:30

Add to Calendar ▼2022-06-22 09:30:002022-06-22 10:30:00Europe/LondonOrgan-on-Chip Models For Medical ApplicationsOrganoids and Organs-on-Chips Europe 2022 in Rotterdam, The NetherlandsRotterdam, The

Organ-on-chip (OoC) platforms are currently considered as the next-generation in vitro models for various fields of applications such as drug and toxicity screening, disease modeling, tissue regeneration, metabolic studies, etc. Key advantages offered by these models compared to standard alternatives like 3D cell culture, are, for instance: (i) the possibility to accurately control the cellular microenvironment; (ii) to implement dynamic culture conditions in a microfluidic format; (iii) to emulate the architecture and/or the function of targeted organs by combining specific microfabricated structures with cells; and (iv) to stimulate the cells in the device, e.g., chemically, mechanically, and electrically, with an excellent spatiotemporal control.

In my presentation I will present current work from the group in the field of cancer research, and the implementation of biomechanical cues in OoCs, notably for the development of a cartilage model.

Add to Calendar ▼2022-06-21 00:00:002022-06-22 00:00:00Europe/LondonOrganoids and Organs-on-Chips Europe 2022Organoids and Organs-on-Chips Europe 2022 in Rotterdam, The NetherlandsRotterdam, The