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SELECTBIO Conferences Lab-on-a-Chip, Microfluidics & Microarray World Congress

Steve Blair's Biography

Steve Blair, Professor, University of Utah

Steve Blair received the B.S. and M.S. degrees in Applied Optics from Rose-Hulman Institute of Technology, Terre Haute, IN, in 1991 and 1993, respectively, and the Ph.D. degree in Electrical Engineering from the University of Colorado, Boulder, in 1998. Since 1998, he has been with the Electrical and Computer Engineering Department, University of Utah, Salt Lake City, and is now an Associate Professor. His research interests include plasmonics, microarray technology and applications, and optical methods for neural stimulation.

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Plasmonic-Enhanced Single-Molecule Detection

Friday, 19 September 2014 at 10:45

Add to Calendar ▼2014-09-19 10:45:002014-09-19 11:45:00Europe/LondonPlasmonic-Enhanced Single-Molecule DetectionLab-on-a-Chip, Microfluidics and Microarray World Congress in San Diego, California, USASan Diego, California,

The next generation of molecular diagnostics tools are targeted to have single molecule sensitivity. Plasmonic-enhanced fluorescence can be a key enabling factor in achieving this goal. Large-scale arrays of plasmonic structures meet the requirements of enhanced signal-to-background in fluorescence detection, along with compatibility with existing instrumentation and surface chemistry. Fluorescence enhancement results from a combination of plasmonic mediated excitation and emission enhancement. Even though molecules are confined within a plasmonic structure, the spectral region of enhancement depends strongly on the metal. As such, have also been working with structures in Al, which is mass-production friendly and provides balanced enhancement throughout the visible spectrum, opening up a wider range of applications. However, new chemical passivation strategies need to be devised due to the native oxide of Al. Tuning of the relative enhancements can be accomplished by adjusting the shape of the plasmonic structures, opening up the UV spectral range where the native fluorescence of biomolecules can be accessed.

Add to Calendar ▼2014-09-18 00:00:002014-09-19 00:00:00Europe/LondonLab-on-a-Chip, Microfluidics and Microarray World CongressLab-on-a-Chip, Microfluidics and Microarray World Congress in San Diego, California, USASan Diego, California,