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SELECTBIO Conferences Flow Chemistry European Summit 2023

Thomas Wirth's Biography

Thomas Wirth, Professor, Cardiff University

Thomas Wirth is professor of organic chemistry at Cardiff University. After studying chemistry in Bonn, he obtained his PhD and at the Technical University of Berlin. After a postdoctoral stay at Kyoto University, he started his independent research at the University of Basel before taking up his current position at Cardiff University in 2000. He was invited as a visiting professor to several places. Thomas Wirth was awarded the Werner-Prize from the New Swiss Chemical Society, the Furusato award from JSPS London, the Wolfson Research Merit Award from the Royal Society and the Bader Award from the Royal Society of Chemistry. In 2016 he was elected as a fellow of The Learned Society of Wales. His main interests of research concern stereoselective electrophilic reactions, oxidative transformations with hypervalent iodine reagents including mechanistic investigations and organic synthesis performed in microreactors.

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Accelerating Biphasic Biocatalysis Through Continuous Flow

Tuesday, 28 March 2023 at 09:30

Add to Calendar ▼2023-03-28 09:30:002023-03-28 10:30:00Europe/LondonAccelerating Biphasic Biocatalysis Through Continuous FlowFlow Chemistry European Summit 2023 in Rotterdam, The NetherlandsRotterdam, The

Process intensification through continuous flow reactions has increased the production rates of fine chemicals and pharmaceuticals. Product generation in segmented flow systems is significantly faster than in traditional batch reactors, which is exemplified in high yield esterifications and in the sesquiterpene cyclase-catalyzed synthesis of sesquiterpenes from farnesyl diphosphate as high-value natural products with applications in medicine, agriculture and the fragrance industry. Product release in sesquiterpene synthases is rate limiting due to the hydrophobic nature of sesquiterpenes, but a biphasic system allows for highly efficient reactions. Results on enzyme immobilization and applications of this strategy towards the synthesis of artemisinin are also shown.

Add to Calendar ▼2023-03-27 00:00:002023-03-28 00:00:00Europe/LondonFlow Chemistry European Summit 2023Flow Chemistry European Summit 2023 in Rotterdam, The NetherlandsRotterdam, The