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SELECTBIO Conferences Point-of-Care Diagnostics & Biosensors Europe 2018

Martyn Boutelle's Biography



Martyn Boutelle, Professor of Biomedical Sensors Engineering, Vice Chair Department of Bioengineering, Imperial College London

Martyn Boutelle is Professor of Biomedical Sensors Engineering, and Deputy Departmental Chair at the Department of Bioengineering, Imperial College London. His research group is genuinely multidisciplinary comprising, bioengineers, scientists and clinicians. He develops novel analytical science methods using microfluidics, electrochemical sensors and biosensors, and wireless electronics to make portable, wearable monitoring devices. He then uses these in a program of clinical science research focusing on the acute traumatic brain injury, kidney transplantation and athelete monitoring. The same measurement techniques are used in patients and in experimental models allowing genuine translational research. Professor Boutelle is a Fellow of the Royal Society of Chemistry. He obtained a BSc and PhD in Chemistry from Imperial College and worked as an EP Abraham Research Fellow in the University of Oxford.

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Towards Wearable Real-Time Clinical Monitoring Using Microfluidic Devices

Tuesday, 5 June 2018 at 09:00

Add to Calendar ▼2018-06-05 09:00:002018-06-05 10:00:00Europe/LondonTowards Wearable Real-Time Clinical Monitoring Using Microfluidic DevicesPoint-of-Care Diagnostics and Biosensors Europe 2018 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com

Modern acute critical care medicine is increasingly seeking to protect vulnerable tissue from damage by monitoring the patterns of physical, electrical and chemical changes taking place in tissue – so called multimodal monitoring. Such patterns of molecular changes offer the exciting possibility of allowing clinicians to detect changes in patient condition and to guide therapy on an individualized basis in real time. Microfluidic lab-on-chip devices coupled to tissue sampling using microdialysis provide an important new way for measuring real-time chemical changes as the low volume flow rates of microdialysis probes are ideally matched to the length scales of microfluidic devices. In this presentation, I will describe the combination of miniature electrochemical sensors and biosensors with 3D printed microfluidic devices for transplant organ and patient monitoring. Concentrations of key biomarker molecules can then be determined continuously using either optically or electrochemically, using amperometric, potentiometic and array sensors.  Wireless devices allow analysis to take place close to the patient. Droplet-based microfluidics, by digitizing the dialysis stream into discrete low volume samples, both minimizes dispersion allowing very rapid concentration changes to be measured, and allows rapid transport of samples between patient and analysis chip. This talk will overview successful design, optimization, automatic-calibration and use of both continuous flow and droplet-based microfluidic analysis systems for real-time clinical monitoring, using clinical examples from our recent work.


Add to Calendar ▼2018-06-05 00:00:002018-06-06 00:00:00Europe/LondonPoint-of-Care Diagnostics and Biosensors Europe 2018Point-of-Care Diagnostics and Biosensors Europe 2018 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com