
Selective Amplification of Rare Mutant Sequences in Samples Containing Abundant Wild-type SequencesWednesday, 14 May 2014 at 17:15 ![]() SuperSelective primers, by virtue of their unique design, employ thermodynamic and kinetic principles that enable the routine quantitation of as few as 10 mutant molecules in samples containing 1,000,000 wild-type molecules, even if the mutation is only a single-nucleotide polymorphism. |