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SELECTBIO Conferences Organ-on-a-Chip and Body-on-a-Chip: In Vitro Systems Mimicking In Vivo Functions "Track A"

John Wikswo's Biography



John Wikswo, Gordon A. Cain University Professor, A.B. Learned Professor of Living State Physics; Founding Director, Vanderbilt Institute for Integrative Biosystems, Vanderbilt University

John Wikswo is the Gordon A. Cain University Professor at Vanderbilt University and is the founding Director of the Vanderbilt Institute for Integrative Biosystems Research and Education. Trained as a physicist, he received his B.A. degree from the University of Virginia, and his PhD. from Stanford University. He has been on the Vanderbilt faculty since 1977. His research has included superconducting magnetometry, the measurement and modeling of cardiac, neural and gastric electric and magnetic fields, and non-destructive testing of aging aircraft. His group’s current work on organ-on-chips focuses on the development of intelligent well plates that serve as perfusion controllers, microclinical analyzers, and microformulators; developing a blood-brain-barrier and a cardiac tissue construct on a chip; and integrating multiple organs to create a milli-homunculus from coupled organs on chips. As a tenured member of the Departments of Biomedical Engineering, Molecular Physiology & Biophysics, and Physics & Astronomy, he is guiding the development of microfabricated devices, optical instruments, and software for studying how living cells interact with each other and their environment and respond to drugs, chemical/biological agents, and other toxins, thereby providing insights into systems biology, physiology, medicine, and toxicology. He has over 200 publications, is a fellow of seven professional societies, and has received 24 patents.

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Scientific, Engineering, and Translational Intersections and Trajectories: Organs-on-Chips, Organoids, Stem Cells, Microfluidics, Well Plates, Acoustics, and Multi-Omics

Friday, 5 October 2018 at 11:00

Add to Calendar ▼2018-10-05 11:00:002018-10-05 12:00:00Europe/LondonScientific, Engineering, and Translational Intersections and Trajectories: Organs-on-Chips, Organoids, Stem Cells, Microfluidics, Well Plates, Acoustics, and Multi-OmicsSELECTBIOenquiries@selectbiosciences.com

As organs-on-chips, organoids, induced pluripotent stem cells, and multi-omics become more widely integrated into the breadth of biology, pharmacology, and toxicology, it is important to understand the intrinsic capabilities and limitations of each approach and their supporting technologies, how they compete with or complement each other, what questions each is best suited to answer, and the associated challenges and opportunities. A comparison should consider issues of spatial scale, cost, sensitivity, ease of use, and assay speed. Economically significant choices, for example between high and low throughput approaches, single versus multiple organs or tissues, and targeted versus untargeted multi-omic analyses, depend upon the questions being asked, the budget, and the anticipated value of the answers. Ultimately, the greatest return on the substantial investment in these technologies may be amplified by a better understanding of technological and scientific intersections and trajectories and how to optimize the translation of each approach to address pressing scientific and medical questions.


Add to Calendar ▼2018-10-04 00:00:002018-10-05 00:00:00Europe/LondonOrgan-on-a-Chip and Body-on-a-Chip: In Vitro Systems Mimicking In Vivo Functions "Track A"SELECTBIOenquiries@selectbiosciences.com