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SELECTBIO Conferences Extracellular Vesicles 2022: Technologies Driving Biological Investigations

Sunitha Nagrath's Biography



Sunitha Nagrath, Professor of Chemical Engineering and Biomedical Engineering, University of Michigan-Ann Arbor

Dr. Sunitha Nagrath (Fellow of AIMBE) is a Professor of Chemical Engineering and Biomedical Engineering at University of Michigan. She received her Ph.D. in 2004 from Rensselaer Polytechnic Institute, Troy, NY in Mechanical Engineering. She did her postdoctoral work at Harvard Medical/Massachusetts General Hospital, Boston, MA. Dr. Nagrath is the leading scientist who designed the MEMS based technology, “CTC-Chip” for the sensitive isolation of circulating tumor cells (CTCs) from the blood of cancer patients. She joined University of Michigan in 2010, where she established her laboratory focused on engineering innovative microfluidic devices and nanomaterials for implementing personalized precision medicine via liquid biopsy. Dr. Nagrath’s major focus of research is on understanding cancer progression and metastasis through isolation, characterization and study of circulating cells and extracellular vesicles. Dr. Nagrath is the co-founder and the board member of labyrinth Biotech., a biotechnology company commercializing some of the technologies that are developed in her lab.

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Microfluidic Technologies for the Isolation and Characterization of Extracellular Vesicles For Lung Cancer Theranostics

Wednesday, 14 December 2022 at 14:30

Add to Calendar ▼2022-12-14 14:30:002022-12-14 15:30:00Europe/LondonMicrofluidic Technologies for the Isolation and Characterization of Extracellular Vesicles For Lung Cancer TheranosticsExtracellular Vesicles 2022: Technologies Driving Biological Investigations in Long Beach, CaliforniaLong Beach, CaliforniaSELECTBIOenquiries@selectbiosciences.com

The extracellular vesicle (EV) has emerged as one of the diagnostic means of cancer through liquid biopsy. So far, ultracentrifugation has been accepted as gold standard for EV isolation in spite of its lengthy processing time and low recovery rate. Owing to the recent technological advances in microfluidics, several microfluidic devices for EV isolation have been developed and showed promising with better recovery rate and processing time. Here we present microfluidic based approaches to isolate and profile tumor derived EVs. To demonstrate the harvesting of EVs from specific cells for therapeutic use we have developed a microfluidic based strategy to harvest EVs from Natural Killer (NK) cells in blood circulation. In combination we have developed theranostics application of EVs in lung cancer.


Add to Calendar ▼2022-12-12 00:00:002022-12-14 00:00:00Europe/LondonExtracellular Vesicles 2022: Technologies Driving Biological InvestigationsExtracellular Vesicles 2022: Technologies Driving Biological Investigations in Long Beach, CaliforniaLong Beach, CaliforniaSELECTBIOenquiries@selectbiosciences.com