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SELECTBIO Conferences Lab-on-a-Chip, Microfluidics & Microarrays World Congress 2016

Abraham Lee's Biography



Abraham Lee, William J. Link Professor and Chair, University of California-Irvine

Abraham (Abe) P. Lee is the William J. Link Chair and Professor of the Department of Biomedical Engineering (BME) with a joint appointment in Mechanical and Aerospace Engineering (MAE) at the University of California at Irvine in the USA. He is also founding director of the Micro/nano Fluidics Fundamentals Focus (MF3) Center. Prior to joining the UCI faculty in 2002, he was a program manager in the Microsystems Technology Office of the Defense Advanced Research Projects Agency (DARPA) (1999-2001). From 1992 to 1999, Dr. Lee was a research engineer and group leader at the Lawrence Livermore National Lab. Dr. Lee’s current research is focused on the development of biomedical microfluidic technologies. These microfluidic tools are applied in large-scale DNA analysis, stem cell biology, point-of-care diagnostics, 3-D vascularized tissue, and "cell-like vesicles" for theranostics. Dr. Lee currently serves as associate editor of the Lab on a Chip journal. He has 38 issued US patents and over 80 peer-reviewed journal papers. Professor Lee was awarded the 2009 Pioneers of Miniaturization Prize by Corning and Lab on a Chip and is an elected fellow of the American Institute of and Medical and Biological Engineering (AIMBE) and the American Society of Mechanical Engineers (ASME). Dr. Lee received his Ph.D. from UC Berkeley in 1992 and his B.S. degree from National Tsing Hua University in 1986.

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Chip-Scale Microfluidic Physiological Circulation Systems

Tuesday, 27 September 2016 at 17:55

Add to Calendar ▼SELECTBIOenquiries@selectbiosciences.com

There has been a recent surge in the development of microphysiological systems and organ-on-a-chip for drug screening and regenerative medicine.  Over the years, drug screening has mostly been carried out on 2D monolayers in well plates and the drugs are not delivered through blood vessels as in vivo treatments. Through the advancement of microfluidics technologies, we have enabled the automation of biological fluids delivery through physiological vasculature networks that mimic the physiological circulation of the human body.  The critical bottleneck is to engineer the microenvironment for the formation of vascularized 3D tissues and to also pump and perfuse the tissue vascular network for on-chip microcirculation.  This in vitro model system can be used to screen cancer drugs by mimicking the delivery of the drugs through capillary blood vessels.  On the other hand, microfluidics play an important role in the recent advances in liquid biopsy and the ability to specifically isolate and capture rare cells such as circulating tumor cells. These two technologies may go hand-in-hand to connect in vitro screening to in vivo screening with great potential in the development of personalized medicine.

Chip-Scale Microfluidic Physiological Circulation Systems

Tuesday, 27 September 2016 at 17:55

Add to Calendar ▼SELECTBIOenquiries@selectbiosciences.com

There has been a recent surge in the development of microphysiological systems and organ-on-a-chip for drug screening and regenerative medicine.  Over the years, drug screening has mostly been carried out on 2D monolayers in well plates and the drugs are not delivered through blood vessels as in vivo treatments. Through the advancement of microfluidics technologies, we have enabled the automation of biological fluids delivery through physiological vasculature networks that mimic the physiological circulation of the human body.  The critical bottleneck is to engineer the microenvironment for the formation of vascularized 3D tissues and to also pump and perfuse the tissue vascular network for on-chip microcirculation.  This in vitro model system can be used to screen cancer drugs by mimicking the delivery of the drugs through capillary blood vessels.  On the other hand, microfluidics play an important role in the recent advances in liquid biopsy and the ability to specifically isolate and capture rare cells such as circulating tumor cells. These two technologies may go hand-in-hand to connect in vitro screening to in vivo screening with great potential in the development of personalized medicine.


Add to Calendar ▼2016-09-26 00:00:002016-09-28 00:00:00Europe/LondonLab-on-a-Chip, Microfluidics and Microarrays World Congress 2016Lab-on-a-Chip, Microfluidics and Microarrays World Congress 2016 in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com