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SELECTBIO Conferences Antibodies in Drug Discovery

Patrick Chames's Biography

Patrick Chames, Main Scientist, INSERM

Patrick Chames, 44 yo, obtained his phD at the "University de la Méditerranée", Marseille, France in 1997 in the field of antibody engineering. From 1997 to 2001, he worked in the laboratory of phage display pioneer Hennie R. Hoogenboom where he isolated by phage display the first human antibody fragment specifically binding to a cancer related class I MHC complex (TCR-like antibodies). From 2001 to 2005, he worked as a project leader for a french start-up company (Cellectis SA, Paris) in the field of genome engineering where he significantly contributed to the set up of an in vivo method, leading to the isolation of homing endonucleases capable of performing specific double strand break in a whole genome. In 2005 he accepted a permanent position for the French National center for research (CNRS). Since 2009, he is working for the French institute for health and medical research (INSERM, Marseille, France) in the field of therapeutic bispecific antibodies and blocking antibodies and is specialized in the use of single domain antibodies. His records include 50 peer reviewed publications and 7 patents.

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Single Domain Antibodies: From Conformational Sensors to Bispecific Antibodies for Immunotherapy

Tuesday, 9 February 2016 at 16:15

Add to Calendar ▼2016-02-09 16:15:002016-02-09 17:15:00Europe/LondonSingle Domain Antibodies: From Conformational Sensors to Bispecific Antibodies for ImmunotherapyAntibodies in Drug Discovery in Cambridge, UKCambridge,

We are using single domain antibodies as innovative tools. Biosensors which are able to capture the conformation states of some membrane receptors such as EGFR or mGluRs, or as building blocks to create bispecific immune modulators.

Add to Calendar ▼2016-02-09 00:00:002016-02-10 00:00:00Europe/LondonAntibodies in Drug DiscoveryAntibodies in Drug Discovery in Cambridge, UKCambridge,