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SELECTBIO Conferences Lab-on-a-Chip and Microfluidics Europe 2023

Valérie Taly's Biography

Valérie Taly, CNRS Research Director, Professor and Group leader Translational Research and Microfluidics, Université Paris Cité

V. Taly is a CNRS research director and group leader of the Translational Research And Microfluidics team within the clinical oncology research unit MEPPOT (personalized medicine pharmacogenomics and therapeutic optimization) in the Cordeliers Research Center (university Paris Cité). Her team performs interdisciplinary researches aiming at developing and validating microfluidic tools for cancer research in close collaboration with clinicians and researchers in oncology and toxicology. Since 2008, she developed droplet-based digital procedures for Cancer diagnosis. Recently, her research has been dedicated to the clinical validation of droplet-based microfluidics for the non-invasive detection of Cancer biomarkers, the highlighting of new Cancer Biomarkers and the development of original tools and procedures for their detection with applications in personalized medicine, cancer recurrence detection and cancer diagnostics. She is co-founder of EMULSEO (2018) and METHYS DX (2021) start up companies.

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Liquid Biopsy Follow-Up of Cancer Patients

Monday, 19 June 2023 at 11:15

Add to Calendar ▼2023-06-19 11:15:002023-06-19 12:15:00Europe/LondonLiquid Biopsy Follow-Up of Cancer PatientsLab-on-a-Chip and Microfluidics Europe 2023 in Rotterdam, The NetherlandsRotterdam, The

Technological developments; such as ddPCR or optimized NGS, have greatly facilitated the tracking of circulating cell-free nucleic acids in body effluents. Several strategies can be designed to detect and characterize circulating tumor DNA (ctDNA) using ddPCR. Examples of such strategies will be presented that are based either cancer-specific methylation markers or DNA integrity evaluation. We will then illustrate the pertinence of these approaches for the detection and monitoring of ctDNA in plasma (so-called liquid biopsy) of patients with localized or advanced cancers. Results of several prospective clinical studies will be presented.

Add to Calendar ▼2023-06-19 00:00:002023-06-20 00:00:00Europe/LondonLab-on-a-Chip and Microfluidics Europe 2023Lab-on-a-Chip and Microfluidics Europe 2023 in Rotterdam, The NetherlandsRotterdam, The