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SELECTBIO Conferences Circulating Biomarkers World Congress 2018

Mike Makrigiorgos's Biography

Mike Makrigiorgos, Professor of Radiation Oncology, Dana Farber Cancer Institute and Harvard Medical School

Dr. Makrigiorgos is a Professor of Radiation Oncology and Director of the Medical Physics & Biophysics division at Dana Farber Cancer Institute and Brigham and Women’s Hospitals, Harvard Medical School. He also directs his DNA technology laboratory and the radiation pre-clinical facility. His research interests include the development of novel DNA technologies for molecular diagnostics in Oncology and the identification of circulating cancer biomarkers. Dr. Makrigiorgos is the inventor of several PCR-based techniques for molecular diagnostics, including Balanced-PCR, NaME-PrO technology and COLD-PCR. He is a Member of the Editorial Board of Clinical Chemistry and has published over 150 articles, reviews and book chapters. He received his undergraduate degree in Physics from the University of Athens, Greece, his PhD in Medical Physics from the University of Leeds, UK and his postdoctoral training in radiation biology from Harvard Medical School, Boston.

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Novel Technologies For the Detection of Clinically Relevant DNA Alterations in Circulating DNA

Thursday, 29 March 2018 at 08:00

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With the increasing interest in treatment assessment using circulating DNA, sensitive and multiplexed detection of tumor-derived alterations in blood are desirable. We provide novel mutation enrichment-based methods that (a) enable several orders of magnitude improvement of microsatellite instability or mutations than currently possible; (b) are highly multiplex-able; (c) reduce the cost of both sample preparation and re-sequencing.  Application in circulating DNA from clinical cancer samples will be presented.

Add to Calendar ▼2018-03-28 00:00:002018-03-29 00:00:00Europe/LondonCirculating Biomarkers World Congress 2018Circulating Biomarkers World Congress 2018 in Boston, USABoston,