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SELECTBIO Conferences Bioengineering for Building Microphysiological Systems 2022

Valeria Orlova's Biography

Valeria Orlova,

Dr. Orlova is recognised for her research on hiPSC applications to cardiovascular biology, disease modelling and blood vessels in organ-on-chip devices. She has a strong background in vascular biology with expertise that includes differentiation of endothelial cells, pericytes, vascular smooth muscle cells and inflammatory cells from hPSCs, assays for functional chararcterization of hPSC-derived vascular cells (inflammatory responses, barrier function, high-content intracellular Ca2+ release), photopatterning technology to design cell substrates, RNAseq and methods for 3D analysis of hiPSC-EC vessels in OoCs. Orlova coordinates a large interdisciplinary consortium funded by the Dutch Research Agenda: Research on Routes by Consortia (NWA-ORC 2019) in which ‘organ-on-chip' models for the lymphatic and immune system are being built using hiPSC as a precision tool to investigate immune system-related disorders.

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