The Effects of ASC-Exosome on Dermatitis
Sun Jae Kwon,
Director,
ExoCoBio Exosome Institute, ExoCoBio Inc.
Exosome from human adipose tissue-derived mesenchymal stem cells (ASC-EXOSOME) was isolated from the serum-free conditioned media by sequential filtration and characterized as recommended by the International Society for Extracellular Vesicles (ISEV). Previously, we revealed that the ASC-EXOSOME alleviates the atopic dermatitis in an inflammatory murine model through down-regulation of multiple cytokine mRNA expression. As a subsequent study, we further analyzed the effects of ASC-EXOSOME on an alternative murine model of atopic dermatitis. The effects of ASC-EXOSOME on the skin barrier function will be presented and discussed.
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