Monday, 28 June 202100:00 | Title to be Confirmed.
Holger Schmidt, Narinder Kapany Professor of Electrical Engineering, University of California-Santa Cruz, United States of America
| 00:00 |  Single-Button Nucleic Acid Extraction for Rapid, Reliable Molecular Testing
Richard Chasen Spero, CEO, Redbud Labs
There are myriad exciting microfluidic platforms for molecular analysis, but few are designed to work with raw samples. We describe a new initiative at Redbud Labs to enable single-button sample preparation on a microfluidic cartridge, focusing on nucleic acid extraction for amplification and sequencing applications. Our method combines gold-standard laboratory biochemistry with cartridge-ready™ chips, MXR™DryPak and STR™BeadPak, to deliver lab-quality yield, fast runtimes, and compact design. We will also share strategies employed to develop our platform on a highly compressed timeline.
| 00:00 |  | Keynote Presentation Title to be Confirmed.
Moran Bercovici, Associate Professor, Faculty of Mechanical Engineering; Head, Technion Microfluidic Technologies Laboratory, Technion, Israel Institute of Technology, Israel
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| 00:00 | Title to be Confirmed.
Alf Månsson, Professor, Linnaeus University and Lund University Sweden, Sweden
| 00:00 | Title to be Confirmed.
Dermot Diamond, Professor, Principal Investigator, Insight Centre for Data Analytics, National Centre for Sensor Research, Dublin City University, Ireland
| 00:00 |  How 3D Printing Small Parts Can Deliver Large Value
John Kawola, CEO, Global Operations, Boston Micro Fabrication (BMF)
Recent advancements in additive manufacturing have focused printing larger and larger parts, but many of the world’s products are getting smaller and smaller. One major limitation in the trend towards smaller products is the inability to use traditional manufacturing methods to cost effectively prototype and produce the small parts. Learn how a unique process called Projection Micro Stereolithography (PµSL) for 3D printing is creating true microstructures with ultra-high printing resolution (2µm~50µm) and printing tolerance (+/- 10µm ~ +/- 25µm).
| 00:00 |  | Conference Chair Title to be Confirmed.
Nicole Pamme, Professor in Analytical Chemistry, The University of Hull, United Kingdom
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| 00:00 |  | Conference Chair Title to be Confirmed.
Thomas Laurell, Professor, Lund University, Sweden
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| 00:00 |  | Keynote Presentation Title to be Confirmed.
Valérie Taly, CNRS Research Director, Group leader Translational Research and Microfluidics, University Paris Descartes, France
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| 00:00 |  | Keynote Presentation Designing a Bioreagent-Compatible Material for a 3D-Printed Molecular Design System
Noah Malmstadt, Professor, Mork Family Dept. of Chem. Eng. & Mat. Sci., University of Southern California, United States of America
While stereolithographic 3D printing (SLA) is a promising method for the rapid prototyping and manufacturing of microfluidic systems, the bioadhesive properties of cured SLA resins are poorly characterized. Adhesion of biomolecules to microfluidic channels is an issue in nearly all biological applications, but it becomes a particular problem in applications that require precise and reproducible control of reaction conditions. Over the past several years, we have deployed SLA-printed modular microfluidic components to automate the biochemical workflow of mRNA display. mRNA display is a selection technology that harnesses a massive oligonucleotide-peptide hybrid library to identify molecules that bind to protein targets; automating the mRNA display workflow is a route towards the rapid development of novel cancer protein binding agents. A major roadblock to the microfluidic automation of mRNA display is the nonspecific adhesion of the many required enzyme, peptide, and oligonucleotide reagents to the channel surfaces.
To minimize or eliminate this adhesion, we have explored a range of SLA resin formulations based on vinyl monomers with various functional groups. After examining the achievable resolution and mechanical properties of each formulation, we characterized peptide, oligonucleotide, and protein adhesion and determined the degree to which adhered enzymes retained enzymatic activity. Low-adhesion SLA-printed modules were assembled to construct an automated system capable of producing new mRNA display binding ligands. |
| 00:00 |  | Keynote Presentation Title to be Confirmed.
Arben Merkoçi, ICREA Professor and Director of the Nanobioelectronics & Biosensors Group, Institut Català de Nanociencia i Nanotecnologia (ICN2), Barcelona Institute of Science and Technology (BIST), Spain
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| 00:00 |  | Keynote Presentation Title to be Confirmed.
Dino Di Carlo, Professor and Vice Chair of Bioengineering, University of California-Los Angeles, United States of America
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| 00:00 | Microfluidic Droplet Reactors to Reveal the Bacterial Interaction in an Antibiotic Environment
Xinne Zhao, Researcher, Helmholtz-Zentrum Dresden Rossendorf, Germany
A microfluidic droplet reactor is designed to track the survival status of co-cultured sensitive and resistant-strains in an antibiotic environment to reveal the possible interaction that happens between two strains. |
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Add to Calendar ▼2021-06-28 00:00:002021-06-30 00:00:00Europe/LondonLab-on-a-Chip and Microfluidics Europe 2021Lab-on-a-Chip and Microfluidics Europe 2021 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
