Lab-on-a-Chip World Congress Agenda

Registration

Tubeless Microfluidic Systems for Personalized Chemotherapy
Albert Folch, Professor of Bioengineering, University of Washington, United States of America

Presently, oncologists do not directly assess tumor chemosensitivity prior to choosing a chemotherapeutic regimen, resulting in inefficient therapies. Here we show a multiplexed microfluidic assay that utilizes intact tumor tissue and could be used to rapidly predict tumor chemosensitivity to a large panel of drugs prior to initiation of therapy.

Microfluidic chips for photo- and radiochemistry
Nicole Pamme, Professor in Analytical Chemistry, Stockholm University, Sweden

Miniaturising chemical processing to the microfluidic scale allows for precise control of reaction conditions. Two examples of efficient microfluidic chemistry are presented: (i) photo-chemistry for light initiated reactions and (ii) radiochemistry for dose-on-demand PET imaging tracers.

Preparation of Nucleic Acid Libraries for Personalized Sequencing Systems Using an Integrated Microfluidic Hub Technology
Kamlesh Patel, R&D Advanced System Engineering and Deployment Manager, Sandia National Laboratories, United States of America

Integrated Digital Microfluidic Hub for Automating Library Construction for Next generation Sequencing Systems

Coffee Break & Networking in Exhibition Hall

Stable Capillary Stop Valves in Highly Hydrophilic Materials for Passive Microfluidic Systems
Marko Blom, Chief Technical Officer, Micronit Microtechnologies, Netherlands

At Micronit Microfluidics, we have fabricated passive capillary stop valves in untreated hydrophilic glass although the general design can be applied to any highly hydrophilic material. These valves demonstrate stable stopping of capillary pressure driven liquid. The valves can be triggered on demand for sequential flow microfluidic applications such as lab-on-a-chip immunoassay.

Microfluidic Tools for Personal Exposure Assessment
Charles Henry, Professor and Chair, Colorado State University, United States of America

This talk will focus on recent work in our laboratory focused on developing paper-based analytical devices for analysis of pollutants in aerosolized particulate matter at the personal level.

Technology Spotlight:
Customer Project “Heart Check” and Manufacturing of LOC / Microfluidic components with different technologies for Medical Products.
Harald Denz, MD & CEO,


This is about a heart test instrument to be used at home for the customer and the results transmitted via GPRS to the house doctor. The cooperation with the customer was to support the development of the technical implementation of LOC plastic components during development in the technical implementation to support. The company itself develops technologies in her own technology center which allow manufacturing components with increasingly finer and thinner structures. The mirror surfaces in the plastic injection molding tools support the use of lasers in research and applications of microfluidics.

Lunch & Networking in Exhibition Hall

Poster Viewing Session

Microfluidics for Engineering 3D Tissues and Cellular Microenvironments
Brian Gillette, Post Doctoral Fellow, Columbia University, United States of America

This presentation describes several methods that integrate microfluidics and 3D biomaterials for engineering tissues and in vitro cellular microenvironments for applications in regenerative medicine and biological studies.

Coffee Break & Networking in Exhibition Hall

Microchip Electrophoresis: On-Animal Sensors and Single Cell Analysis
Susan Lunte, Professor, University of Kansas, United States of America

Microdialysis sampling combined with microchip electrophoresis yields a separation-based sensor that can be used to continuously monitor neurotransmitters and nitric oxide metabolites in awake freely roaming animals. The very fast separations achievable with these devices also make it possible to detect labile reactive nitrogen species in single cells.

Microfluidic Digital Logic for the Autonomous Lab-on-a-Chip
Elliot Hui, Associate Professor of Biomedical Engineering, University of California-Irvine, United States of America

We are building digital microcontrollers entirely out of microfluidic components, without electronics, allowing controls to be integrated with fluid handling on a self-contained chip. We demonstrate a clock, a finite-state machine controller, and a metering and mixing circuit.

A Linear Array of Unique Microfluidic Gradients for Enzymatic Bioassay
Matthew Estes, Postdoctoral Research Associate, Center for Applied NanoBioscience and Medicine, University of Arizona, United States of America

The authors present a single chip capable of generating a linear array of unique diffusion-based gradients in a variety of microchannels in parallel.

Drinks Reception

Inertial Microfluidic Devices for Cell Separations
Ian Papautsky, Professor, University of Cincinnati, United States of America

Separation and isolation of cells from a mixture remains to be a critical technical challenge, especially when cells are rare.  This talk will focus on inertial microfluidic devices for continuous separation of cell mixtures with high selectivity and throughput.

Microelectronics Meets Microfluidics: Hybrid Integration of Sensors in Microfluidic Devices
Holger Becker, Chief Scientific Officer, Microfluidic ChipShop GmbH, Germany

In addition to the well established optical detection methods, a recent development in lab-on-a-chip technology is the increased use of sensor technology for the detection of analytes in a microfluidic system. These sensors can range from relatively simple electrochemical sensors to electronically read-out microarrays or highly integrated nano-electrode sensors with on-chip signal processing capabilities. These sensors require innovative technological solutions for their integration into a microfluidic cartridge. We will present solutions for such integrated systems for the detection of biomarkers, proteins and nucleic acids for applications in rapid infectious disease identification or drug efficacy monitoring.

Coffee Break & Networking in Exhibition Hall

Five Tips for Successful Commercialization of Lab-on-Chip Diagnostics
Erol Harvey, Chief Executive Officer, MiniFAB, Australia

Successful technology transfer from laboratory prototype to full-scale manufacture of medical diagnostic products is about managing complexity. The growing field of lab-on-chip point-of-care devices is an opportunity growth area. MiniFAB will share five tips for successful commercialization of lab-on-chip diagnostics.

Technology Spotlight:
Enabling Smart Consumable Devices for Biosciences and Diagnostics - Cost Drivers and Technologies
Jessica Melin, Senior Manager, Sony Dadc Austria AG


Providing high quality consumable devices at application compliant cost  is critical for diagnostic platforms. Such devices increasingly demand mass manufactured polymer microstructures. This talk discusses the important interplay between device mass manufacturability, cost drivers, and detection principles.

Lunch & Networking in Exhibition Hall

Poster Viewing Session

Capillarity-based Paper Networks for Automated Point of Care Diagnostics
Barry Lutz, Research Assistant Professor, University of Washington, United States of America

Biochemical diagnostics are typically run in a lab by an expensive instrument or a trained human. We are exploiting properties of shaped paper to “program” disposable devices that run multi-step biochemical diagnostics without an instrument at a cost and ease-of-use comparable to a pregnancy test.

Direct-Write of 3D Functional Biomaterials using Projection Stereolithography
Shaochen Chen, Professor, The University of California San Diego, United States of America

Dr. Chen will discuss a novel digital projection stereolithography microfabrication platform for 3D biomaterial scaffolds, which allows control over properties including stiffness, pore-sizes, Poisson’s ratio in three dimensions for 3D tissue engineering.

Coffee Break & Networking in Exhibition Hall

Micromachining Technologies for Configurable 3D Biochips
Carlotta Guiducci, Professor, Ecole Polytechnique Federale De Lausanne, Switzerland

Configurable electronic biochips with improved robustness towards the wet environment would enable the widespread use of CMOS-based systems in bioanalytics and personalized medicine. An innovative technology for 3D semi-disposable biochips featuring microelectrode arrays is presented.

Close of Conference