Abstract

Accurate Concentration of Biological Nanoparticles – Why and How?

Jean-Luc Fraikin, CEO, Spectradyne

Extracellular vesicles (EVs), virus and non-viral drug delivery vehicles are rapidly moving from the research lab into real-world applications.  Why should we care about measuring the concentration of these biological nanoparticles accurately? In the case of a COVID vaccine for example, we should care because particle concentration is the dose!  In a broad range of applications, particle concentration is a critical parameter that must be carefully controlled in order to develop safe and effective products.  This talk will include a comparison of methods and examples to illustrate how accurate concentration measurements are important for good quality science.