Abstract

Regulation of Extracellular Vesicle Biogenesis In Tissue Repair

Brian Eliceiri, Professor, UC San Diego

Extracellular vesicles (EVs) are released by defined intracellular trafficking machinery that can mediate paracrine signaling that affects immune responses and tissue repair.  Here, specific examples of how specific pathways and genetic models affect EV payloads, and how these payloads can be used to design custom engineered therapeutics.