Abstract

The OptiDrop Microfluidic Analyzer and Sorter: Multiplexed Fluorescence and Scatter Detection with Single Cell Resolution for Droplet Microfluidic Applications

Preksha Gupta, Senior Scientist, Centre for Cellular and Molecular Platforms

The OptiDrop platform is a novel optofluidic technology enabling multiparametric optical analysis and sorting of microfluidic droplets. Current droplet-based assays for multi-omic applications rely on expensive imaging-based methods or complicated flow cytometry based workflows for optical analysis of droplet contents. In a first, the OptiDrop platform combines the simplicity of on-chip fiber optics with the power of flow cytometry to provide multiplexed fluorescence and scatter signals from droplet contents with single cell resolution.