Abstract

3D-Bioprinting Technologies For Tissue Engineering and Organ-on-chip Development

Pierre-Alexandre Laurent, Senior Field Application Specialist, CELLINK

We will present how our 3D bioprinting technologies contribute to the tissue engineering, the organoids research and the organ-on-chip development. We will discuss how CELLINK’s technology enables the large-scale manufacturing of tissue constructs, which have wide application, including the development and validation of the efficacy of pharmaceutical and cosmetic products, screening of drug therapies, understanding of tissue development and oncology processes, and in the future translation to use in clinical applications. In addition, we will introduce our bioinks, which enable researchers to culture human cells to grow into functional tissue constructs. They provide a tissue specific microenvironment that cells can thrive in and allow to tailor a complex multicellular structure furnishing features of functional organs. Finally, we will discuss how cell biology and 3D-bioprinting approaches, are used to print organoids and tissue structures (such as liver, heart, skin), functional cancer tumor models as well as perfusable vascular network.