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SELECTBIO Conferences 3D-Culture & Organoids

Shane Horman's Biography



Shane Horman, Research Investigator, Functional Genomics – Advanced Assays, Genomics Institute of the Novartis Research Foundation

Dr. Shane Horman runs the Advanced Assay group at the Genomics Institute of the Novartis Research Foundation (GNF) in San Diego, California. He received his Ph.D. from King’s College-London in molecular genetics and was a postdoc at the University of Pennsylvania-School of Medicine and then at Cincinnati Children’s Hospital Medical Center investigating mouse models of human leukemias. Dr. Horman’s Advanced Assay group at GNF is dedicated to the development and implementation of complex and 3D high content microphysiological screening platforms that may better reflect in vivo patient biology for early stage drug discovery. Dr. Horman has published numerous papers on high content 3D screening platforms and regularly presents at phenotypic drug discovery conferences.

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High Content Screening of an Antigen-Specific 3D Tumor-Spheroid/Primary T-cell Co-Culture System

Friday, 5 October 2018 at 13:30

Add to Calendar ▼2018-10-05 13:30:002018-10-05 14:30:00Europe/LondonHigh Content Screening of an Antigen-Specific 3D Tumor-Spheroid/Primary T-cell Co-Culture System3D-Culture and Organoids in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com

Overcoming tumor-mediated immunosuppression and enhancing cytotoxic T-cell activity within the tumor microenvironment are two central goals of immuno-oncology (IO) drug discovery initiatives. Here we present a novel ultra-high-content assay platform for interrogating antigen-dependent T-cell-mediated killing of 3D tumor spheroids that yields multi-parametric, clinically-relevant data and can be employed kinetically for the discovery of novel IO therapeutic agents.


Add to Calendar ▼2018-10-04 00:00:002018-10-05 00:00:00Europe/London3D-Culture and Organoids3D-Culture and Organoids in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com