Robert Halliwell,
Professor of Neuroscience,
University of The Pacific
Robert F. Halliwell completed postgraduate training in neurological science at University College London, in pharmacology at Ninewells Hospital & Medical School, University of Dundee and a Post-Doctoral Fellowship in Neuroscience at the University of California, Irvine. I previously held a lectureship in Neuroscience at the University of Durham, England and I am currently Professor in Neuroscience in the School of Pharmacy, University of the Pacific. I contribute to Schools of Neuroscience in Africa for IBRO; I am a member of the Medical Ethics Committee at St Joseph’s Medical Center, Stockton, CA, and an Advisor on Mental Health for the Wellness Center of San Joaquin County. My laboratory is addressing the properties and value of neurons derived from a variety of human stem cells for studies in neuropharmacology and neurotoxicology; I have also published work in the history of medicine.
Exploiting Human Stem Cells to Assess Risk of Developmental Neurotoxicity from Psychotropic Drugs
Friday, 14 June 2019 at 11:30
Add to Calendar ▼2019-06-14 11:30:002019-06-14 12:30:00Europe/LondonExploiting Human Stem Cells to Assess Risk of Developmental Neurotoxicity from Psychotropic Drugs3D-Culture, Organoids and Tox Screening Europe 2019 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
The developing human nervous system is highly susceptible to damage from environmental agents including heavy metals, organophosphate pesticides and pharmaceutical agents including psychotropic drugs. Determining the risk of neurotoxicity in humans using animal models is not very reliable. Our lab has been pioneering the study of human stem cells as a model of neurogenesis to address development neurotoxicity from psychotropic agents in vitro. This presentation will describe the experiments we are conducting investigating a variety of human stem cells, including tissue (adult) and induced pluripotent stem (iPS) cells to derive functional neurons. I will present the morphological, immunocytochemical, electrophysiological and neuropharmacological properties of neurons derived from human stem cells. I will also describe the impact of a range of psychotropic agents, including a number of antiepileptic medicines on the differentiation and maturation of human stem cells into functional neurons in vitro. Finally, I will present data on the value of human stem cell-derived neurons in the study of neuroprotection.
Add to Calendar ▼2019-06-13 00:00:002019-06-14 00:00:00Europe/London3D-Culture, Organoids and Tox Screening Europe 20193D-Culture, Organoids and Tox Screening Europe 2019 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com