Noo Li Jeon is a Professor of School of Mechanical and Aerospace Engineering at Seoul National University (SNU). He studied Materials Science and Engineering at Northwestern University (B.S.) and University of Illinois Urbana-Champagne (Ph.D.). He worked on soft lithography applications in Prof G.M. Whitesides’ laboratory at Harvard University and at Prof M. Toner’s group at Harvard Medical School. He was an Associate Professor at UC Irvine from 2001-2009 in the Department of Biomedical Engineering. In 2009, he moved to Seoul National University to join School of Mechanical Engineering at Seoul National University.
Vascularized Tumor Spheroids for Drug Screening on Injection Molded IMPACT Platform
Thursday, 13 June 2019 at 09:30
Add to Calendar ▼2019-06-13 09:30:002019-06-13 10:30:00Europe/LondonVascularized Tumor Spheroids for Drug Screening on Injection Molded IMPACT Platform3D-Culture, Organoids and Tox Screening Europe 2019 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
The field of microfluidics-based three-dimensional (3D) cell culture systems is rapidly progressing from academic proof-of-concept studies to valid solutions to real-world problems. Polydimethylsiloxane (PDMS)-based microfluidics platforms have been widely adopted for tumor-on-a-chip systems. However, due to the inherent material limitations that make it difficult to scale-up production, PDMS has not been widely used in standardized commercial applications for preclinical screening testing. In this presentation, injection-molded tumor spheroid chip made of polystyrene (PS) in a standardized 96-well plate format with a user-friendly design. Spontaneous liquid patterning is achievable with high repeatability. To demonstrate the feasibility of the device, we fabricated array of vascularized tumor spheroids and developed a 3D tumor angiogenesis model for drug screening. This model is easy- and ready-to-use, and suitable for mass-production systems, with the ability to deliver robust and reproducible results.
Add to Calendar ▼2019-06-13 00:00:002019-06-14 00:00:00Europe/London3D-Culture, Organoids and Tox Screening Europe 20193D-Culture, Organoids and Tox Screening Europe 2019 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2019-06-13 09:30:002019-06-13 10:30:00Europe/LondonVascularized Tumor Spheroids for Drug Screening on Injection Molded IMPACT Platform3D-Culture, Organoids and Tox Screening Europe 2019 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
