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SELECTBIO Conferences ADMET Europe

David Hay's Biography



David Hay, Chair of Tissue Engineering, MRC Centre for Regenerative Medicine, University of Edinburgh

David is the Professor of Tissue Engineering at the University of Edinburgh. Dave has worked in the field of stem cell biology and differentiation for over fifteen years. He and his team have highlighted the important role that pluripotent stem cells have to play in modelling human liver biology ‘in the dish’ and supporting failing liver function in vivo. The impact of this work has led to a number of peer-reviewed publications (>100), regular appearances at high profile conferences, and three start-up companies.

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A Bio-active Polymer Promotes Stem Cell Derived Hepatocyte Inducible Drug Metabolism

Monday, 28 March 2011 at 10:00

Add to Calendar ▼2011-03-28 10:00:002011-03-28 11:00:00Europe/LondonA Bio-active Polymer Promotes Stem Cell Derived Hepatocyte Inducible Drug MetabolismADMET Europe in MunichMunichSELECTBIOenquiries@selectbiosciences.com

The generation of hepatic endoderm (HE) from human embryonic stem cells (hESCs) represents a viable route with which to generate a scalable resource for drug and toxicology testing. However, like primary human hepatocytes, hESC-derived HE demonstrates limited viability and phenotypic stability on the current state of the art tissue culture substratum, matrigel. To overcome issues of phenotypic stability and viability we have screened a polymer library and identified a defined supporting basement matrix.


Add to Calendar ▼2011-03-28 00:00:002011-03-29 00:00:00Europe/LondonADMET EuropeADMET Europe in MunichMunichSELECTBIOenquiries@selectbiosciences.com