Shopping Cart (0)
My Account

Shopping Cart
SELECTBIO Conferences ADMET Europe

Monika Vastag's Biography



Monika Vastag, Laboratory Head, Gedeon Richter Plc

Monika Vastag is a senior researcher in the department of pharmacology and drug safety research of Gedeon Richter plc and head of in vitro metabolism laboratory. She has over ten years of experience in the drug development industry. She graduated as biological engineer in Budapest University of Technology in 1989 and received a Ph.D. degree in 2000 from Semmelweis School of Medicine on the field of research blood-brain barrier. She worked as post doc at the department of Neuropathology, University School of Miami, and as a senior research scientist at the Physiological Institute, Ludwig Maximilian University Munich. Main research interests include BBB models for CNS drug testing, drug metabolism and interaction. She has published 20 research articles including one review and 2 book chapters and edited one book.

Monika Vastag Image

Morphological and Functional Characterization of Cell-Based BBB Penetration Models

Monday, 28 March 2011 at 11:45

Add to Calendar ▼2011-03-28 11:45:002011-03-28 12:45:00Europe/LondonMorphological and Functional Characterization of Cell-Based BBB Penetration ModelsADMET Europe in MunichMunichSELECTBIOenquiries@selectbiosciences.com

Cell-based models, like the triple co-culture model using brain derived cells, and models using MDCKII-MDRI, Caco-2 or the recently introduced VB-Caco-2 cultures can be used as cell-based tools to predict brain penetration of new drug candidates. This talk compares the critical morphological and functional features of cell-based models, using in-house generated data, which contribute towards differing/similar permeability functions.


Add to Calendar ▼2011-03-28 00:00:002011-03-29 00:00:00Europe/LondonADMET EuropeADMET Europe in MunichMunichSELECTBIOenquiries@selectbiosciences.com