Reverse Identification Disposition Mechanisms in Drug Candidate ProfilingMonday, 28 March 2011 at 17:00 Add to Calendar ▼2011-03-28 17:00:002011-03-28 18:00:00Europe/LondonReverse Identification Disposition Mechanisms in Drug Candidate ProfilingADMET Europe in MunichMunichSELECTBIOenquiries@selectbiosciences.com The presentation will focus on how divergent non-clinical drug disposition, efficacy and safety data could be reconciled by a systematic revision of preclinical profiling in combination with targeted supplemental in vivo and in vitro studies. The importance of optimal versus minimal ADME screening and the necessity to pursue the mechanisms of surprising advantageous as well as disadvantageous ADME/PK profiling data will be discussed. |