Joanne Nettleship's Biography

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Streamlining the Pipeline Towards Glycoprotein Structures

Thursday, 30 June 2011 at 17:00

Add to Calendar ▼2011-06-30 17:00:002011-06-30 18:00:00Europe/LondonStreamlining the Pipeline Towards Glycoprotein StructuresSELECTBIOenquiries@selectbiosciences.com

• High-throughput pipeline for glycoprotein production in HEK 293 cells. • Parallelization and automation of expression screening. • Glycan modification to aid glycoprotein crystallization. • Automated large scale production and purification of secreted proteins. • Use of transient transfection v’s formation of a stable cell line. • Antibody Fab’s as co-crystallization chaperones. • In situ diffraction for solving glycoprotein structures.