Conferences \ BioProcessing, Biologics & Biotherapeutics Congress \ Antibody and Peptide Therapeutics \ Agenda \ Jonas Schaefer |
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Folding and Aggregation of IgGs - Influence of Mutations and Expression SystemsWednesday, 20 July 2011 at 17:00 Add to Calendar ▼2011-07-20 17:00:002011-07-20 18:00:00Europe/LondonFolding and Aggregation of IgGs - Influence of Mutations and Expression SystemsSELECTBIOenquiries@selectbiosciences.com Framework mutations have previously shown to greatly influence folding and stability of scFv expressed in bacteria. While analyzing the effects of different eukaryotic expression systems as well as various antibody formats, similarities and differences in antibody biosynthesis and characteristics were encountered and will be presented. |