Timothy Kassis's Biography

Timothy Kassis, Researcher, DARPA-PhysioMimetics Program, Massachusetts Institute of Technology (MIT)

Timothy Kassis is a research associate working with professor Linda Griffith in the Biological Engineering department at MIT where, along with a larger team, works on a DARPA funded project to build a physiologically relevant model of 10 interacting organs for use in drug development and physiological in vitro research. Timothy Kassis obtained his B.Eng in electrical engineering from the University of Nottingham, an M.S. in mechanical engineering from the Georgia Institute of Technology and his Ph.D. in Bioengineering from the Georgia Institute of Technology where he used various in vivo imaging approaches to study the functional role of lymphatic vessels in lipid absorption and transport. Timothy’s research interests revolve around developing next generation in vitro research tools for gaining unprecedented clinical and biological insights.

Luncheon Presentation: A Vascularized Endocrine Pancreas Microphysiological System

Friday, 17 March 2017 at 13:30

Add to Calendar ▼2017-03-17 13:30:002017-03-17 14:30:00Europe/LondonLuncheon Presentation: A Vascularized Endocrine Pancreas Microphysiological SystemSELECTBIOenquiries@selectbiosciences.com

Diabetes has reached epidemic proportions and is on a steep rise globally. A hallmark of diabetes is characterized by dysfunctional pancreatic islets. These pancreatic islets are a spherical aggregate of around 20 different cell types with the beta cells being the main type of cell implicated in the disease. Islets are highly vascularized and it has been shown that both the blood flow through this vasculature as well as endothelial cell-signaling are critical components in regulating beta cells and how they produce insulin in response to glucose. The authors developed a vascularized pancreas microphysiological system (MPS) that can potentially be used to study human islet physiology and pathophysiology within a relevant 3D physiological microenvironment, with the ability to connect the MPS to a 7-organ interaction platform to build a ‘human-on-a-chip’ for diabetes research. The authors believe that their platform will provide researchers with an invaluable tool to study pancreatic islets in both health and disease.

Add to Calendar ▼2017-03-16 00:00:002017-03-17 00:00:00Europe/LondonBioMEMS, Microfluidics and Biofabrication: Technologies and ApplicationsSELECTBIOenquiries@selectbiosciences.com

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