Characterization of Cell-Based Assays for use with 3D Culture Models to Determine the Mechanism of CytotoxicityTuesday, 22 January 2013 at 14:45 Add to Calendar ▼2013-01-22 14:45:002013-01-22 15:45:00Europe/LondonCharacterization of Cell-Based Assays for use with 3D Culture Models to Determine the Mechanism of CytotoxicitySELECTBIOenquiries@selectbiosciences.com A variety of 3-dimensional cell culture approaches are emerging as candidates to represent more physiologically relevant models for in vitro toxicity testing. Although many convenient add-mix-measure cell-based assay protocols exist to interrogate markers of cytotoxicity, most protocols were designed for use on cells grown as monolayers or as a suspension cultures. There is a need to verify the validity of metabolic indicators used as markers of cell health as well as the performance of standard assays with increasingly complex 3D model systems. |