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SELECTBIO Conferences Companion Diagnostics

Matthew Marton's Biography



Matthew Marton, Director, Merck Research Laboratories

Matthew Marton is Director of Clinical Genomics in Merck & Co.’s Molecular Biomarkers & Diagnostics department, where his team has deployed predictive biomarkers as patient enrichment assays on multiple technology platforms in over a dozen Merck clinical studies. His current work focuses on the CoDx strategy of novel genomic assays as molecular diagnostics, and he is a contributor to several CLSI documents involving molecular diagnostic testing in oncology. Prior work at Merck focused on technology/method development and biomarker discovery, with an emphasis on quality control of molecular profiling assays. Earlier in his career, Dr. Marton worked with Drs. Stephen Friend and Lee Hartwell at the Seattle Project, a drug discovery think tank, which led to the founding of Rosetta Inpharmatics, a biotechnology company that was acquired by Merck in 2001. At Rosetta and subsequently at Merck, he led scientific efforts to create a GLP-like high throughput functional genomics laboratory. Dr. Marton completed post-doctoral training at the NIH and holds a PhD from Princeton University and a Certificate in Biomedical Regulatory Affairs from the University of Washington.

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The Development of Regulated Next Generation Sequencing-based Clinical Trial Assays and Companion Diagnostics

Tuesday, 28 October 2014 at 12:00

Add to Calendar ▼2014-10-28 12:00:002014-10-28 13:00:00Europe/LondonThe Development of Regulated Next Generation Sequencing-based Clinical Trial Assays and Companion DiagnosticsSELECTBIOenquiries@selectbiosciences.com

Topics Addressed based on the Following:

Pant, S., Weiner, R. and Marton, MJ.  Navigating the Rapids : The Development of Regulated Next Generation Sequencing-based Clinical Trial Assays and Companion Diagnostics. 2014.  Frontiers in Oncology. 17 April 2014 | doi: 10.3389/fonc.2014.00078.

Chang, C.N., Kang, J, Qiu, P., Pant, S., Wei, B., Weiner, R and Marton, MJ.  Validation of Next Generation Sequencing Cancer Panels for Clinical Mutation Profiling-- Identification of Source of Variations and Artifactual Mutations using FFPE Tissues.  2014.  Submitted to Journal of Next Generation Sequencing and Applications.

Chang, C.N. and Marton, MJ.  Past, Current and Future Approaches to Querying MAPK Pathway Activation – Status and Clinical Implications.  2014.  Submitted to Future Medicine.

Chang, C.N., Galuska, S., Weiner, R. and M.J. Marton.  Development and Validation of a Clinical Trial Patient Stratification Assay that Interrogates 27 Mutation Sites in MAPK Pathway Genes.  2013.  PLoS One. 2013 Aug 21;8(8):e72239. doi: 10.1371/journal.pone.0072239.


Add to Calendar ▼2014-10-27 00:00:002014-10-28 00:00:00Europe/LondonCompanion DiagnosticsSELECTBIOenquiries@selectbiosciences.com