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SELECTBIO Conferences CellTech 2013

Matthew Croughan's Biography

Matthew Croughan, Professor and Director of the Amgen Bioprocessing Center at KGI, Kecks Graduate Institute

Matt Croughan is the George B. and Joy Rathmann Professor and Director of the Amgen Bioprocessing Center at Keck Graduate Institute (KGI). He founded the Bioprocessing focus track at KGI and has built it into one of the largest masters-level programs in bioprocessing, with a unique emphasis on recruiting and educating the next generation of business leaders in bioprocessing. As the sole full time faculty member in bioprocessing at KGI, he teaches eight graduate courses and advises 30-40 masters and two doctoral students specializing in various areas of bioprocessing. Prior to joining KGI, and still one day per week, Dr. Croughan works as an independent consultant providing expert guidance on biopharmaceutical process development and manufacturing to over fifty firms. Previously Dr. Croughan was the chief scientist for Genentech’s cell culture facility in Vacaville, CA, built for the production of therapeutic antibodies. Earlier in his career at Genentech, he developed the first high-density, fed-batch cell culture process, a breakthrough platform technology now used throughout the biopharmaceutical industry. Matt has a Ph.D. from MIT and a BS from UC Berkeley, both in chemical engineering.

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Development and Scale-up of Transient Gene Expression at 300 mg/L from CHO Cells

Tuesday, 22 January 2013 at 09:00

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This talk will cover new approaches that achieve titers of 300 mg/L from transient gene expression (TGE) using CHO cells.   Engineering challenges unique to TGE that arise upon scale-up, including mixing and mass transport during the transfection step, are successfully addressed using scale down models and engineering analyses.

Add to Calendar ▼2013-01-22 00:00:002013-01-23 00:00:00Europe/LondonCellTech 2013CellTech 2013 in San Diego, CA, USASan Diego, CA,