Takahiro Ochiya's Biography

Takahiro Ochiya, Professor, Department of Molecular and Cellular Medicine, Tokyo Medical University

Dr. Takahiro Ochiya was a Chief of Division of Molecular and Cellular Medicine at the National Cancer Center Research Institute, Tokyo since 2011 and he is currently appointed as professor of Tokyo Medical University (since 2018). After he got Ph.D. in 1988 in Osaka University and then went to do a post-doc at La Jolla Cancer Research (Burnham Institute for Medical Research), CA, USA. Dr. Ochiya’s lab focuses the development of novel animal models, methods, and strategies to study cancer development and metastasis. Especially, current focuses are siRNA- and microRNA-based therapy against cancer stem cells. Dr. Ochiya is one of top scientist in Exosome research in cancer area and carries President of Japanese Society of Extracellular Vesicles (JSEV) since 2014.

Chemically Induced Liver Progenitors as a Source for Liver Regeneration and Organ Reconstruction

Friday, 7 December 2018 at 10:30

Add to Calendar ▼2018-12-07 10:30:002018-12-07 11:30:00Europe/LondonChemically Induced Liver Progenitors as a Source for Liver Regeneration and Organ ReconstructionCell Therapy Asia 2018 in Kobe, JapanKobe, JapanSELECTBIOenquiries@selectbiosciences.com

We currently report that a cocktail of small molecules can convert rat and mouse MHs in vitro into proliferative bipotent cells, which we term chemically induced liver progenitors (CLiPs) (Katsuda et al., Cell Stem Cell, 2017). CLiPs can differentiate into both mature hepatocytes and biliary epithelial cells that can form functional ductal structures. CLiPs in long-term culture did not lose their proliferative capacity or their hepatic differentiation ability, and rat CLiPs were shown to extensively repopulate chronically injured liver tissue. Our current progress on generation of human CLiPs from human mature hepatocytes and the therapeutic potency for liver diseases as well as potency of drug metabolism and towards organ reconstruction will be mentioned.

Add to Calendar ▼2018-12-06 00:00:002018-12-07 00:00:00Europe/LondonCell Therapy Asia 2018Cell Therapy Asia 2018 in Kobe, JapanKobe, JapanSELECTBIOenquiries@selectbiosciences.com

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