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Applications of Mesenchymal Stem Cells for Cosmetic Product Development and Translational Regenerative Medicine

Tuesday, 22 April 2014 at 09:45

Add to Calendar ▼2014-04-22 09:45:002014-04-22 10:45:00Europe/LondonApplications of Mesenchymal Stem Cells for Cosmetic Product Development and Translational Regenerative MedicineClinical Translation of Stem Cells 2014 in Palm Springs, California, USAPalm Springs, California, USASELECTBIOenquiries@selectbiosciences.com

Mesenchymal stem cells (MSCs) are defined as undifferentiated cells that are capable of self-renewal and differentiation into several cell types such as chondrocyte, adipocyte, osteocyte, myocyte, hepatocyte, and neuron-like cells. Moreover, MSCs express several extracellular matrix (ECM) molecules such as collagen, fibronectin, laminin, and proteoglycans. Furthermore, MSCs can yield a series of cytokines and signal molecules that can suppress inflammatory responses such as IL-1 receptor antagonists and can upregulate anti-inflammatory cytokines such as IL-10 and IL-6. Unlike conventional skin care products can only slow down the aging process, biological formula (Bioliquid) derived from MSCs are able to stimulate cellular repair and regeneration. Compared to the other ingredients, Stem Cell Bioliquid with better absorption and penetration effect can revitalize skin by enhancing healthy cell proliferation and improving the rate of cell metabolism. The skin care products with the addition of Stem Cell Skin Bioliquid will be beneficial in obtaining the anti-aging effect equivalent to accept the top-level cosmetic rejuvenation medical treatment.
Our company – DrSignal also aims to accelerate the translation of laboratory research from stem cell and molecular biology into the clinical regenerative medicine. It is the first time that a novel injectable bio-graft which composed of MSCs (gingival stem cells and adipocyte stem cells), bone cement (calcium sulfate powder) and Stem Cell Bone Bioliquid, was developed for the applications of bone regeneration. In the animal model, we can engineer a scaled-up ossified tissue with features of a “bone organ,” including physiologically corticale bone, mature vasculature, and a hematopoietic compartment by using the injectable bio-graft. This work provides a model helpful for the applications of translational bone regeneration on the alveolar bone augmentation in dental implant surgery.