Conformational Flexibility in Drug Design of Anti-apoptotic Proteins InhibitorsWednesday, 19 February 2014 at 14:15 Add to Calendar ▼2014-02-19 14:15:002014-02-19 15:15:00Europe/LondonConformational Flexibility in Drug Design of Anti-apoptotic Proteins InhibitorsDiscovery Chemistry Congress in Barcelona, SpainBarcelona, SpainSELECTBIOenquiries@selectbiosciences.com Inhibitors derived from the natural compound meiogynine A, targeting the anti-apoptotic proteins Bcl-xL and Mcl-1, were designed using virtual screening of focused ligand libraries on selected representative protein conformations generated by all-atom molecular dynamics simulations. |